Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | ALDH1A3 | P47895 | 3/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25229335 | 0.98 | ALDH1A1 (0.53) | ALDH1A1ALDH1A3ALDH3A1VCAM1HSD17B10 | |
| SCHEMBL6212368 | 0.85 | ALDH1A1 (0.55) | ALDH1A1ALDH1A3ALDH3A1VCAM1HSD17B10 | |
| SCHEMBL7189747 | 0.82 | ALDH1A1 (0.57) | ALDH1A1ALDH1A3ALDH3A1VCAM1HSD17B10 | |
| SCHEMBL3324475 | 0.81 | ALDH1A1 (0.52) | ALDH1A1ALDH1A3ALDH3A1VCAM1HSD17B10 | |
| SCHEMBL11374196 | 0.81 | ALDH1A1 (0.55) | ALDH1A1ALDH1A3ALDH3A1VCAM1HSD17B10 | |
| SCHEMBL13044803 | 0.81 | ALDH1A1 (0.55) | ALDH1A1ALDH1A3ALDH3A1VCAM1HSD17B10 | |
| SCHEMBL3240034 | 0.80 | ALDH1A1 (0.50) | ALDH1A1ALDH1A3ALDH3A1VCAM1HSD17B10 | |
| SCHEMBL21773462 | 0.80 | ALDH1A1 (0.50) | ALDH1A1ALDH1A3ALDH3A1VCAM1HSD17B10 | |
| Water SCHEMBL10953352 | 0.79 | ALDH1A1 (0.53) | ALDH1A1ALDH1A3ALDH3A1VCAM1HSD17B10 | |
| SCHEMBL6364244 | 0.78 | L3MBTL1 (0.55) | ALDH1A1ALDH1A3HSD17B10PTGS2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001049660-A1 | A PROCESS FOR PREPARING 3-{[3-CHLORO-4-(METHYLSULFONYL)-PHENYL]METHYLENE}-2,4-PENTANEDIONE | ORION CORPORATION (FI) | 2001-07-12 | — | — | WO | claimed |
| US-20250059220-A1 | SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AND METHODS OF USE THEREOF | MERCK SHARP & DOHME LLC (US) | 2025-02-20 | — | — | US | disclosed |
| WO-2023121939-A1 | SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AND METHODS OF USE THEREOF | MERCK SHARP & DOHME LLC (US) | 2023-06-29 | — | — | WO | disclosed |
| WO-2023121939-A1 | SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AND METHODS OF USE THEREOF | MERCK SHARP & DOHME LLC (US) | 2023-06-29 | — | — | WO | disclosed |
| US-10717734-B2 | Indole and azaindole haloallylamine derivative inhibitors of lysyl oxidases and uses thereof | PHARMAXIS LTD. (AU) | 2020-07-21 | — | — | US | disclosed |
| US-20200069648-A1 | HALOALLYLAMINE PYRAZOLE DERIVATIVE INHIBITORS OF LYSYL OXIDASES AND USES THEREOF | PHARMAXIS LTD. (AU) | 2020-03-05 | — | — | US | disclosed |
| US-20200069648-A1 | HALOALLYLAMINE PYRAZOLE DERIVATIVE INHIBITORS OF LYSYL OXIDASES AND USES THEREOF | PHARMAXIS LTD. (AU) | 2020-03-05 | — | — | US | disclosed |
| CN-110709385-A | Haloallylamine pyrazole derivative inhibitors of lysyl oxidase and uses thereof | 法玛西斯有限公司 | 2020-01-17 | — | — | CN | disclosed |
| US-20190119269-A1 | INDOLE AND AZAINDOLE HALOALLYLAMINE DERIVATIVE INHIBITORS OF LYSYL OXIDASES AND USES THEREOF | PHARMAXIS LTD. (AU) | 2019-04-25 | — | — | US | disclosed |
| WO-2018157190-A9 | HALOALLYLAMINE PYRAZOLE DERIVATIVE INHIBITORS OF LYSYL OXIDASES AND USES THEREOF | PHARMAXIS LTD. (AU) | 2018-10-25 | — | — | WO | disclosed |
| CN-1780832-A | 5-phenylthiazole derivatives and their use as PI3 kinase inhibitors | NOVARTIS AG (CH) | 2006-05-31 | — | — | CN | disclosed |
| EP-1608647-A1 | 5-PHENYLTHIAZOLE DERIVATIVES AND THEIR USE AS P13 KINASE INHIBITORS | Novartis AG (CH) | 2005-12-28 | — | — | EP | disclosed |
| US-20050171131-A1 | Diaminopyrimidine derivatives as growth hormone secrectgogue receptor (GHS-R) antagonists | KOSOGOF CHRISTI (US) | 2005-08-04 | — | — | US | disclosed |
| WO-2004078754-A1 | 5-PHENYLTHIAZOLE DERIVATIVES AND THEIR USE AS P13 KINASE INHIBITORS | NOVARTIS AG (CH) | 2004-09-16 | — | — | WO | disclosed |
| EP-1091933-B1 | SUBSTITUTED BETA-DIKETONES AND THEIR USE | ORION CORP (FI) | 2003-11-26 | — | — | EP | disclosed |
| WO-2001049660-A1 | A PROCESS FOR PREPARING 3-{[3-CHLORO-4-(METHYLSULFONYL)-PHENYL]METHYLENE}-2,4-PENTANEDIONE | ORION CORPORATION (FI) | 2001-07-12 | — | — | WO | disclosed |
| WO-2001049660-A1 | A PROCESS FOR PREPARING 3-{[3-CHLORO-4-(METHYLSULFONYL)-PHENYL]METHYLENE}-2,4-PENTANEDIONE | ORION CORPORATION (FI) | 2001-07-12 | — | — | WO | disclosed |
| EP-1091933-A1 | SUBSTITUTED $g(b)-DIKETONES AND THEIR USE | ORION CORPORATION (FI) | 2001-04-18 | — | — | EP | disclosed |
| US-6201027-B1 | NONSTEROIDAL ANTIINFLAMMATORY DRUG FOR PROPHYLAXIS AND TREATMENT OF RESPIRATORY SYSTEM DISORDERS, I.E. ASTHMA, IN STEROID-RESISTANT MAMMALS | ORION CORPORATION (FI) | 2001-03-13 | — | — | US | disclosed |
| WO-2000001667-A1 | SUBSTITUTED β-DIKETONES AND THEIR USE | ORION CORPORATION (FI) | 2000-01-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171131-A1 | Diaminopyrimidine derivatives as growth hormone secrectgogue receptor (GHS-R) antagonists | GHSR, GIPR, GPR119 | ALDH1A1 2435/4885ALDH1A3 2985/4885ALDH3A1 1667/4885 |
| US-10717734-B2 | Indole and azaindole haloallylamine derivative inhibitors of lysyl oxidases and uses thereof | IDO1, IDO2, INMT | ALDH1A1 322/4885ALDH1A3 979/4885ALDH3A1 211/4885 |
| US-20250059220-A1 | SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AND METHODS OF USE THEREOF | SULT1E1, TPMT, SULT1A1 | ALDH1A1 211/4885ALDH1A3 743/4885ALDH3A1 777/4885 |
| US-20200069648-A1 | HALOALLYLAMINE PYRAZOLE DERIVATIVE INHIBITORS OF LYSYL OXIDASES AND USES THEREOF | LOX, DAO, AADAC | ALDH1A1 301/4885ALDH1A3 858/4885ALDH3A1 135/4885 |
| US-20190119269-A1 | INDOLE AND AZAINDOLE HALOALLYLAMINE DERIVATIVE INHIBITORS OF LYSYL OXIDASES AND USES THEREOF | IDO1, IDO2, INMT | ALDH1A1 322/4885ALDH1A3 979/4885ALDH3A1 211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.