Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 13/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7099787 | 0.81 | CHRNA7 (0.45) | CNR1CNR2 | |
| SCHEMBL7013326 | 0.75 | CNR1 (0.42) | CNR1CNR2 | |
| SCHEMBL7555526 | 0.72 | CNR1 (0.51) | CNR1CNR2 | |
| SCHEMBL8206314 | 0.71 | CNR1 (0.45) | CNR1CNR2 | |
| Hydrochloric Acid SCHEMBL8214654 | 0.70 | CNR1 (0.44) | CNR1CNR2 | |
| SCHEMBL15881111 | 0.69 | HSD11B1 (0.53) | — | |
| SCHEMBL8218668 | 0.68 | NPC1 (0.59) | — | |
| SCHEMBL7519048 | 0.68 | CHRNA7 (0.50) | CNR1CNR2 | |
| Hydrochloric Acid SCHEMBL8216489 | 0.67 | NPC1 (0.58) | — | |
| SCHEMBL8221080 | 0.67 | MAPT (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102769-B1 | TRICYCLIC CARBOXAMIDES | SMITHKLINE BEECHAM PLC (GB) | 2003-04-16 | — | — | EP | claimed |