Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CCR2 | P41597 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | WDR5 | P61964 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2017068 | 0.84 | LMNA (0.43) | L3MBTL1HSD11B1CES1S1PR2S1PR4 | |
| SCHEMBL7591942 | 0.80 | ALDH1A1 (0.43) | L3MBTL1LMNAALDH1A1 | |
| SCHEMBL27492603 | 0.80 | KMT2A (0.38) | HSD11B1CES1LMNAALDH1A1WDR5 | |
| SCHEMBL3277048 | 0.80 | HSD11B1 (0.50) | HSD11B1CCR2ALDH1A1 | |
| SCHEMBL29639823 | 0.77 | EPAS1 (0.45) | L3MBTL1EPAS1LMNAHTTNPSR1 | |
| SCHEMBL28939203 | 0.77 | EPAS1 (0.45) | L3MBTL1EPAS1LMNAHTTNPSR1 | |
| SCHEMBL31453874 | 0.76 | L3MBTL1 (0.44) | L3MBTL1S1PR2S1PR4S1PR3EPAS1 | |
| SCHEMBL9343399 | 0.76 | L3MBTL1 (0.44) | L3MBTL1S1PR2S1PR4S1PR3EPAS1 | |
| SCHEMBL7972629 | 0.74 | HTT (0.46) | L3MBTL1HSD11B1LMNACCR2ALDH1A1 | |
| SCHEMBL699706 | 0.74 | HPGD (0.35) | L3MBTL1HSD11B1S1PR2S1PR4S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110922367-A | Intermediate of topramezone and preparation method of topramezone | 江苏中旗科技股份有限公司 | 2020-03-27 | — | — | CN | disclosed |
| EP-2325176-B1 | Process for the preparation of Isoxazolin-3-yl-Acylbenzenes | BASF SE (DE) | 2015-02-25 | — | — | EP | disclosed |
| EP-2298749-B1 | Process for the preparation of Thioethers | BASF SE (DE) | 2014-12-24 | — | — | EP | disclosed |
| US-8124810-B2 | Preparation of isoxazolin-3-ylacylbenzenes | BASF SE (DE) | 2012-02-28 | — | — | US | disclosed |
| US-8049017-B2 | Preparation of isoxazolin-3-ylacylbenzenes | BASF SE (DE) | 2011-11-01 | — | — | US | disclosed |
| US-20110152535-A1 | PREPARATION OF ISOXAZOLIN-3-YLACYLBENZENES | RHEINHEIMER JOACHIM | 2011-06-23 | — | — | US | disclosed |
| EP-2325176-A1 | Process for the preparation of isoxazolin-3-yl-acylbenzenes | BASF SE (DE) | 2011-05-25 | — | — | EP | disclosed |
| EP-2298749-A1 | Process for the preparation of Thioethers | BASF SE (DE) | 2011-03-23 | — | — | EP | disclosed |
| US-20100105920-A1 | PREPARATION OF ISOXAZOLIN-3-YLACYLBENZENES | BASF SE (DE) | 2010-04-29 | — | — | US | disclosed |
| US-7663001-B2 | Preparation of isoxazolin-3-ylacylbenzene | BASF AKTIENGESELLSCHAFT (DE) | 2010-02-16 | — | — | US | disclosed |
| US-6670482-B2 | Which are used as herbicides, by forming a 2-(isoxazol-3-yl)-aniline compound of given formula and then halogenation, thioalkylation, oxidation and acylation; fewer steps, efficiency | BASF AKTIENGESELLSCHAFT (DE) | 2003-12-30 | — | — | US | disclosed |
| US-20030220505-A1 | Process and novel intermediates for preparing isoxazolin-3-ylacyl benzenes | VON DEYN WOLFGANG (DE) | 2003-11-27 | — | — | US | disclosed |
| US-20030216580-A1 | Preparation of Isoxazolin-3-Ylacylbenzene | BASF SE (DE) | 2003-11-20 | — | — | US | disclosed |
| US-6608209-B2 | Reacting a nitro-o-methylphenyl compound with an organic nitrite in presence of a base to give an oxime, cyclizing the oxime with an alkene in presence of a base to give an intermediate, reducing nitrogroup in presence of catalyst | BASF AKTIENGESELLSCHAFT (DE) | 2003-08-19 | — | — | US | disclosed |
| US-6525204-B1 | Oximination reaction of nitro-o-methylphenyl compound with organic nitrite; cyclization with alkene in basic catalyst presence; reduction, bromination, oxidation, carboxylation | BASF AKTIENGESELLSCHAFT (DE) | 2003-02-25 | — | — | US | disclosed |
| US-20030028033-A1 | Process and novel intermediates for preparing isoxazolin-3-ylacyl benzenes | DEYN WOLFGANG VON (DE) | 2003-02-06 | — | — | US | disclosed |
| US-20030018200-A1 | Preparation of isoxazolin-3-ylacylbenzenes | BASF SE (DE) | 2003-01-23 | — | — | US | disclosed |
| US-6469176-B1 | CROP PROTECTION COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-22 | — | — | US | disclosed |
| EP-1077955-A1 | METHOD FOR PRODUCING ISOXAZOLINE-3-YL-ACYL BENZENE | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058509-A1 | METHOD FOR PRODUCING ISOXAZOLINE-3-YL-ACYL BENZENE | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152535-A1 | PREPARATION OF ISOXAZOLIN-3-YLACYLBENZENES | CBR3, CYP4X1, UQCRB | L3MBTL1 2376/4885HSD11B1 922/4885CES1 603/4885 |
| US-20100105920-A1 | PREPARATION OF ISOXAZOLIN-3-YLACYLBENZENES | CBR3, CYP4X1, UQCRB | L3MBTL1 2376/4885HSD11B1 922/4885CES1 603/4885 |
| US-20030220505-A1 | Process and novel intermediates for preparing isoxazolin-3-ylacyl benzenes | CYP2F1, CBR3, CBR1 | L3MBTL1 3187/4885HSD11B1 507/4885CES1 388/4885 |
| US-20030216580-A1 | Preparation of Isoxazolin-3-Ylacylbenzene | UQCRB, CYP1B1, CYP2F1 | L3MBTL1 2070/4885HSD11B1 877/4885CES1 402/4885 |
| US-20030018200-A1 | Preparation of isoxazolin-3-ylacylbenzenes | CYP2F1, UQCRB, CYP1B1 | L3MBTL1 2147/4885HSD11B1 901/4885CES1 393/4885 |
| US-20030028033-A1 | Process and novel intermediates for preparing isoxazolin-3-ylacyl benzenes | CYP2F1, CBR3, CBR1 | L3MBTL1 3187/4885HSD11B1 507/4885CES1 388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.