Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25277162 | 0.84 | ALDH1A1 (0.50) | NPC1RAB9ACA12CA9ALDH1A1 | |
| SCHEMBL7018101 | 0.83 | L3MBTL1 (0.46) | ALDH1A1LMNAHTT | |
| SCHEMBL7030911 | 0.83 | MMP3 (0.40) | MEN1KMT2ACA12CA9KDM4E | |
| SCHEMBL7026061 | 0.82 | ACHE (0.50) | ALDH1A1LMNAHTTATM | |
| SCHEMBL7026540 | 0.79 | KMT2A (0.56) | MEN1KMT2ANPC1RAB9ACA12 | |
| SCHEMBL7024816 | 0.74 | SMN1; SMN2 (0.49) | LMNAHTT | |
| SCHEMBL23420055 | 0.70 | L3MBTL1 (0.46) | KDM4EALDH1A1LMNA | |
| SCHEMBL18949771 | 0.70 | ALDH1A1 (0.39) | ALDH1A1HPGD | |
| SCHEMBL13308081 | 0.69 | TSHR (0.48) | ALDH1A1 | |
| SCHEMBL990642 | 0.69 | ALDH1A1 (0.61) | RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997474-B1 | Antithrombotic agents | PFIZER (US) | 2003-10-29 | — | — | EP | disclosed |
| US-6417203-B1 | HETEROCYCLIC AMIDES | PFIZER INC. | 2002-07-09 | — | — | US | disclosed |
| US-6180627-B1 | INDOLE, INDAZOLE, BENZOTRIAZOLE AND BENZIMIDAZOLE DERIVATIVES | PFIZER INC. | 2001-01-30 | — | — | US | disclosed |
| EP-0997474-A1 | Antithrombotic agents | PFIZER INC. (US) | 2000-05-03 | — | — | EP | disclosed |