Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7010831 | 0.89 | ALDH1A1 (0.42) | NPSR1ADORA2AADORA1ALDH1A1SMN1; SMN2 | |
| SCHEMBL18321913 | 0.80 | ADORA2A (0.42) | KMT2AMEN1LMNAADORA2AADORA1 | |
| SCHEMBL7019103 | 0.79 | ALDH1A1 (0.49) | KMT2AMEN1LMNANPSR1KDM4E | |
| SCHEMBL7010358 | 0.77 | TP53 (0.44) | MAPK1TSHRLMNAMAPTALDH1A1 | |
| SCHEMBL13257531 | 0.76 | LMNA (0.44) | MAPK1LMNAADORA2AADORA1KDM4E | |
| SCHEMBL13266361 | 0.72 | LMNA (0.38) | KMT2AMEN1LMNAMAPTHSD17B10 | |
| SCHEMBL13258438 | 0.71 | LMNA (0.40) | LMNAADORA2AADORA1KDM4EMAPT | |
| SCHEMBL2566910 | 0.71 | LMNA (0.38) | LMNAMAPTHSD17B10JAK2ALDH1A1 | |
| SCHEMBL13266358 | 0.71 | LMNA (0.45) | KMT2ATSHRMEN1LMNAMAPT | |
| SCHEMBL13257672 | 0.71 | LMNA (0.39) | LMNAHSD17B10ALDH1A1PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733633-B1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0733633-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | disclosed |