SCHEMBL229131

SCHEMBL229131

O=S(=O)(C1CNCCS1)C1CNCCS1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.31
APLNR P35414 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7019044 0.82 MAOA (0.33) MAOA
SCHEMBL4743254 0.82 APLNR (0.41) APLNR
SCHEMBL7348348 0.73 MAOA (0.37) MAOA
SCHEMBL6769741 0.72 HTR6 (0.37) MAOA
SCHEMBL4775469 0.69 MAPT (0.39) MAOA
SCHEMBL1318768 0.67
SCHEMBL29085808 0.64
SCHEMBL15110674 0.62
SCHEMBL209169 0.62
SCHEMBL27529688 0.62 SLC6A1 (0.31) MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1997 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250129085-A1 SUBSTITUTED IMIDAZO[1,2-B]PYRIDAZINES AS PROTEIN KINASE INHIBITORS SUMITOMO PHARMA AMERICA INC (US) 2025-04-24 US claimed
US-9695175-B2 Highly selective c-Met inhibitors as anticancer agents CB THERAPEUTICS INC. (KY) 2017-07-04 US claimed
EP-1685119-B1 N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS ABBVIE BAHAMAS LTD (BS) 2016-03-09 EP claimed
US-20150218171-A1 HIGHLY SELECTIVE C-MET INHIBITORS AS ANTICANCER AGENTS APOLLOMICS INC. 2015-08-06 US claimed
EP-2892904-A1 HIGHLY SELECTIVE C-MET INHIBITORS AS ANTICANCER AGENTS Crown Bioscience Inc. (Taiwan) (CN) 2015-07-15 EP claimed
EP-2340025-B1 CGRP RECEPTOR ANTAGONISTS MERCK SHARP & DOHME (US) 2014-10-15 EP claimed
WO-2014032498-A1 HIGHLY SELECTIVE C-MET INHIBITORS AS ANTICANCER AGENTS CROWN BIOSCIENCE INC. (TAICANG) (CN) 2014-03-06 WO claimed
EP-2308812-B1 N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS ABBVIE BAHAMAS LTD (BS) 2014-02-26 EP claimed
EP-2326176-B1 NON-AMIDIC LINKERS WITH BRANCHED TERMINI AS CGRP RECEPTOR ANTAGONISTS MERCK SHARP & DOHME (US) 2013-09-18 EP claimed
WO-2011150338-A1 METHODS OF TREATING OBESITY ZAFGEN CORPORATION (US) 2011-12-01 WO claimed
EP-1725544-B1 3-[4-HETEROCYCLYL-1,2,3-TRIAZOL-1-YL]-N-ARYL-BENZAMIDES AS INHIBITORS OF THE CYTOKINES PRODUCTION FOR THE TREATMENT OF CHRONIC INFLAMMATORY DISEASES BOEHRINGER INGELHEIM PHARMA (US) 2009-05-27 EP claimed
EP-1066286-B1 HETEROCYCLO-SUBSTITUTED IMIDAZOPYRAZINE PROTEIN TYROSINE KINASE INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2009-04-29 EP claimed
US-7265143-B2 C-4 substituted retinoids UNIVERSITY OF MARYLAND, BALTIMORE (US) 2007-09-04 US claimed
CN-1658873-A New pharmaceutical compositions based on anticholinergics and p38 kinase inhibitors BOEHRINGER INGELHEIM PHARMA (DE) 2005-08-24 CN claimed
CN-1658834-A Method of treating mucus hypersecretion BOEHRINGER INGELHEIM PHARMA (DE) 2005-08-24 CN claimed
EP-0988292-B1 PIPERAZINE DERIVATIVES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS SCHERING AG (DE) 2003-02-12 EP claimed
US-6271235-B1 VIRICIDE AGOURON PHARMACEUTICALS, INC. 2001-08-07 US claimed
EP-0641204-B1 17-ETHERS AND THIOETHERS OF 4-AZA-STEROIDS MERCK & CO INC (US) 2000-08-16 EP claimed
US-20260138966-A1 WNT SIGNALING PATHWAY INHIBITORS FOR TREATMENTS OF DISEASE UNIV OF MARYLAND BALTIMORE (US) 2026-05-21 US disclosed
EP-0390602-A1 Neurotrophic peptides SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1990-10-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150218171-A1 HIGHLY SELECTIVE C-MET INHIBITORS AS ANTICANCER AGENTS MET, MYC, HGFAC MAOA 4142/4885APLNR 1638/4885
US-20250129085-A1 SUBSTITUTED IMIDAZO[1,2-B]PYRIDAZINES AS PROTEIN KINASE INHIBITORS PIM1, PIM2, PIM3 MAOA 3609/4885APLNR 3124/4885
US-20260138966-A1 WNT SIGNALING PATHWAY INHIBITORS FOR TREATMENTS OF DISEASE CTNNB1, WNT1, CTNND1 MAOA 4530/4885APLNR 469/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.