SCHEMBL7019536

SCHEMBL7019536

CCCCOC(C)(OCCCC)OC(C)c1cccc(C(=O)O)c1C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SLC37A4 O43826 1/20 0.40
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
RECQL P46063 1/20 0.38
KMT2A Q03164 1/20 0.38
ALDH1A1 P00352 2/20 0.38
TSHR P16473 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
PTPN11 Q06124 2/20 0.36
CYP3A4 P08684 1/20 0.34
MAPK1 P28482 1/20 0.34
CA12 O43570 1/20 0.34
CA9 Q16790 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2470059 0.91 SLC37A4 (0.38) SLC37A4KDM4EMEN1RECQLKMT2A
SCHEMBL7876590 0.89 SLC37A4 (0.36) SLC37A4KDM4EMEN1RECQLKMT2A
SCHEMBL9011052 0.82 SLC37A4 (0.45) SLC37A4KDM4EMEN1RECQLKMT2A
SCHEMBL28526977 0.81 KDM4E (0.41) SLC37A4KDM4EMEN1RECQLKMT2A
SCHEMBL2470054 0.77 PPARA (0.35) SLC37A4KDM4EMEN1RECQLKMT2A
SCHEMBL3667886 0.75 ALDH1A1 (0.55) KDM4EMEN1RECQLKMT2AALDH1A1
SCHEMBL3374028 0.75 TSHR (0.45) SLC37A4KDM4EMEN1RECQLKMT2A
SCHEMBL7201886 0.74 LMNA (0.40) SLC37A4KDM4EMEN1RECQLKMT2A
SCHEMBL1189460 0.72 ALDH1A1 (0.52) KDM4EMEN1RECQLKMT2AALDH1A1
SCHEMBL9011104 0.72 CA12 (0.43) SLC37A4KDM4EKMT2AALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5795695-A PHOTO-QUALITY RECORDING XEROX CORPORATION (US) 1998-08-18 US claimed
EP-0973811-B1 SELF-LIGHT-STABILIZED PHOTOCHROMIC POLYMER, ITS PREPARATION AND ARTICLES CONTAINING SAME CORNING SA (FR) 2003-01-15 EP disclosed
US-6476103-B1 Photochromic organic material, its manufacture and the photochromic articles containing it CORNING INCORPORATED 2002-11-05 US disclosed
EP-0973811-A4 SELF-LIGHT-STABILIZED PHOTOCHROMIC POLYMER, ITS PREPARATION AND ARTICLES CONTAINING SAME CORNING SA (FR) 2000-07-12 EP disclosed
EP-0973811-A1 SELF-LIGHT-STABILIZED PHOTOCHROMIC POLYMER, ITS PREPARATION AND ARTICLES CONTAINING SAME CORNING INCORPORATED (US) 2000-01-26 EP disclosed
EP-0931278-A4 PHOTOCHROMIC ORGANIC MATERIAL, ITS MANUFACTURE AND THE PHOTOCHROMIC ARTICLES CONTAINING IT CORNING INC (US) 1999-12-29 EP disclosed
EP-0931278-A1 PHOTOCHROMIC ORGANIC MATERIAL, ITS MANUFACTURE AND THE PHOTOCHROMIC ARTICLES CONTAINING IT CORNING INCORPORATED (US) 1999-07-28 EP disclosed
WO-1998045341-A1 SELF-LIGHT-STABILIZED PHOTOCHROMIC POLYMER, ITS PREPARATION AND ARTICLES CONTAINING SAME CORNING INCORPORATED (US) 1998-10-15 WO disclosed
WO-1998016863-A1 PHOTOCHROMIC ORGANIC MATERIAL, ITS MANUFACTURE AND THE PHOTOCHROMIC ARTICLES CONTAINING IT CORNING INCORPORATED (US) 1998-04-23 WO disclosed