Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7445522 | 0.87 | LMNA (0.35) | ACHEBCHEALDH1A1LMNACYP1A2 | |
| SCHEMBL7021973 | 0.87 | BCHE (0.34) | ACHEBCHELMNACYP1A2CYP2D6 | |
| SCHEMBL7014749 | 0.81 | LMNA (0.33) | ACHEBCHEALDH1A1LMNACYP1A2 | |
| SCHEMBL7016988 | 0.74 | CSNK2A2 (0.42) | ACHEBCHEHRH3CYP2C19HTR2C | |
| SCHEMBL7019229 | 0.74 | BCHE (0.38) | ACHEBCHEALDH1A1LMNACYP2D6 | |
| SCHEMBL7021972 | 0.73 | TAAR1 (0.30) | — | |
| SCHEMBL7963781 | 0.71 | MEN1 (0.43) | ACHEBCHEKCNMA1ALDH1A1HRH3 | |
| SCHEMBL8470141 | 0.69 | — | — | |
| SCHEMBL211307 | 0.69 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL7021216 | 0.68 | DDAH1 (0.53) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051415-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-09-24 | — | — | EP | disclosed |
| US-6495542-B1 | SUCH AS 2-METHOXY-N-(2-METHYL-1H-BENZIMIDAZOL-4-YL)-4-(2,3,4,5-TETRAHYDRO-5-OXO-1H-1-BENZAZEPIN-1-YL)CARBONYL-BENZAM IDE; HYPERTENSION, HEART FAILURE, RENAL INSUFFICIENCY, EDEMA, ASCITES, VASOPRESSIN PARASECRETION SYNDROME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-12-17 | — | — | US | disclosed |