Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7019645 | 0.87 | ACHE (0.40) | LMNACYP1A2CYP2D6CYP2C19BCHE | |
| SCHEMBL7021973 | 0.83 | BCHE (0.34) | LMNACYP1A2CYP2D6CYP2C19BCHE | |
| SCHEMBL7014749 | 0.78 | LMNA (0.33) | LMNACYP1A2CYP2D6CYP2C19BCHE | |
| SCHEMBL7021972 | 0.70 | TAAR1 (0.30) | — | |
| SCHEMBL7021216 | 0.68 | DDAH1 (0.53) | LMNATSHRALDH1A1HPGD | |
| SCHEMBL7019229 | 0.68 | BCHE (0.38) | LMNACYP2D6CYP2C19TSHRBCHE | |
| SCHEMBL6197934 | 0.67 | RAB9A (0.50) | LMNACYP1A2CYP2D6CYP2C19TSHR | |
| SCHEMBL7024978 | 0.66 | DDAH1 (0.39) | — | |
| SCHEMBL7016988 | 0.66 | CSNK2A2 (0.42) | CYP2C19TSHRBCHEACHEHTR2C | |
| SCHEMBL8470141 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051415-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999037637-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-07-29 | — | — | WO | disclosed |