Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATG4B | Q9Y4P1 | 12/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 10/20 | 0.44 |
| ▸ | THRA | P10827 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10788245 | 0.79 | IAPP (0.43) | THRATHRBCYP1A2 | |
| SCHEMBL6150486 | 0.79 | ATG4B (0.66) | ATG4BPLA2G1BTHRATHRBCYP1A2 | |
| SCHEMBL8622648 | 0.78 | CNR1 (0.40) | THRBCYP1A2 | |
| SCHEMBL8622651 | 0.78 | CNR1 (0.40) | THRBCYP1A2 | |
| SCHEMBL10950481 | 0.75 | RARB (0.44) | — | |
| SCHEMBL9552417 | 0.72 | ESR1 (0.40) | THRATHRB | |
| SCHEMBL7019684 | 0.72 | MEN1 (0.32) | ATG4BPLA2G1BTHRATHRB | |
| SCHEMBL7019483 | 0.72 | ESR1 (0.41) | — | |
| SCHEMBL7024676 | 0.71 | STS (0.36) | — | |
| SCHEMBL10584455 | 0.70 | MMP2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929509-B1 | LIQUID CRYSTAL ALKENYL BICYCLO 2.2.2]OCTANES AND MIXTURES AND DEVICES CONTAINING SUCH COMPOUNDS | QINETIQ LTD (GB) | 2003-01-15 | — | — | EP | disclosed |