Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | STS | P08842 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.31 |
| ▸ | HSD11B2 | P80365 | 2/20 | 0.31 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.30 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.30 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | CCR2 | P41597 | 1/20 | 0.30 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10950481 | 0.82 | RARB (0.44) | MEN1KMT2A | |
| SCHEMBL11039794 | 0.74 | TSHR (0.49) | STS | |
| SCHEMBL7019483 | 0.73 | ESR1 (0.41) | HSD11B1HSD11B2 | |
| SCHEMBL11044405 | 0.73 | ALDH1A1 (0.49) | STS | |
| SCHEMBL11039459 | 0.73 | ALDH1A1 (0.49) | STS | |
| SCHEMBL7024676 | 0.72 | STS (0.36) | STSHSD11B1HSD11B2IDH1 | |
| SCHEMBL7019681 | 0.72 | ATG4B (0.44) | PLA2G1BATG4BTHRATHRB | |
| Hydrochloric Acid SCHEMBL7027855 | 0.72 | SPHK1 (0.38) | STS | |
| SCHEMBL10584455 | 0.72 | MMP2 (0.46) | HSD11B1HSD11B2 | |
| SCHEMBL6150484 | 0.71 | THRA (0.58) | MEN1KMT2APLA2G1BATG4BTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929509-B1 | LIQUID CRYSTAL ALKENYL BICYCLO 2.2.2]OCTANES AND MIXTURES AND DEVICES CONTAINING SUCH COMPOUNDS | QINETIQ LTD (GB) | 2003-01-15 | — | — | EP | disclosed |