Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP5 | P45974 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 6/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | USP3 | Q9Y6I4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7018357 | 0.80 | MMP1 (0.49) | ALDH1A1KMT2A | |
| SCHEMBL7017112 | 0.75 | MMP2 (0.42) | USP5ALDH1A1MMP2MMP9MMP13 | |
| SCHEMBL942563 | 0.70 | MCHR1 (0.52) | ALDH1A1KMT2AKDM4EDRD2MCHR1 | |
| SCHEMBL21714588 | 0.70 | L3MBTL1 (0.53) | USP5ALDH1A1MMP2MMP9MMP13 | |
| SCHEMBL7023218 | 0.69 | MMP1 (0.53) | ALDH1A1KMT2A | |
| SCHEMBL7373117 | 0.68 | CCR1 (0.41) | CCR1DRD2MCHR1 | |
| SCHEMBL942107 | 0.67 | MMP3 (0.45) | USP5ALDH1A1MMP2MMP9MMP13 | |
| SCHEMBL942579 | 0.66 | TP53 (0.56) | USP5ALDH1A1TP53DRD2MCHR1 | |
| SCHEMBL22581743 | 0.66 | TP53 (0.59) | USP5ALDH1A1KMT2ATP53CCR1 | |
| SCHEMBL7018744 | 0.65 | COMT (0.45) | USP5ALDH1A1SMN1; SMN2CCR1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370536-A1 | METALLOPROTEINASE INHIBITORS | AstraZeneca AB (SE) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002074750-A1 | METALLOPROTEINASE INHIBITORS | ASTRAZENECA AB (SE) | 2002-09-26 | — | — | WO | disclosed |