Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 2/20 | 0.49 |
| ▸ | EDNRB | P24530 | 4/20 | 0.43 |
| ▸ | EDNRA | P25101 | 4/20 | 0.43 |
| ▸ | F10 | P00742 | 10/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.42 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.38 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7023007 | 0.85 | CASP1 (0.54) | CASP1EDNRBEDNRAPRSS1PRSS2 | |
| SCHEMBL8240985 | 0.81 | CASP1 (0.56) | CASP1EDNRBEDNRABCAT2UCHL1 | |
| SCHEMBL10915661 | 0.78 | CASP1 (0.45) | CASP1EDNRBEDNRAPRSS1PRSS2 | |
| SCHEMBL1767981 | 0.78 | CA2 (0.58) | CASP1EDNRBEDNRAUCHL1USP30 | |
| SCHEMBL29537027 | 0.78 | CA2 (0.58) | CASP1EDNRBEDNRAUCHL1USP30 | |
| SCHEMBL5147607 | 0.78 | CASP1 (0.54) | CASP1EDNRBEDNRA | |
| SCHEMBL20528790 | 0.77 | CA9 (0.50) | PRSS1PRSS2PRSS3 | |
| SCHEMBL418847 | 0.77 | CASP1 (0.51) | CASP1EDNRBEDNRAUCHL1USP30 | |
| SCHEMBL1268486 | 0.76 | POLB (0.51) | EDNRAMCL1 | |
| SCHEMBL27567092 | 0.76 | CA1 (0.50) | EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0499096-A1 | Substituted arylsulfonylaminoguanidinotriazines | BAYER AG (DE) | 1992-08-19 | — | — | EP | disclosed |
| CN-1050873-A | The alkylsulfonyl guanylhydrazones that replaces | BAYER AG (DE) | 1991-04-24 | — | — | CN | disclosed |