Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30077664 | 1.00 | KDM4E (0.50) | KDM4EGLAALDH1A1POLBGAA | |
| SCHEMBL30626196 | 1.00 | KDM4E (0.50) | KDM4EGLAALDH1A1POLBGAA | |
| SCHEMBL27650666 | 0.92 | KDM4E (0.50) | KDM4EGLAALDH1A1POLBGAA | |
| SCHEMBL856256 | 0.92 | KDM4E (0.50) | KDM4EGLAALDH1A1POLBGAA | |
| SCHEMBL16117986 | 0.84 | SLC9A1 (0.44) | ALDH1A1POLBGAAHPGDL3MBTL1 | |
| SCHEMBL1047232 | 0.83 | KDM4E (0.57) | KDM4EGLAALDH1A1POLBGAA | |
| SCHEMBL3031603 | 0.83 | CYP3A4 (0.52) | KDM4EGLAALDH1A1POLBGAA | |
| SCHEMBL16636823 | 0.82 | SLC9A1 (0.40) | KDM4EGLAALDH1A1POLBGAA | |
| SCHEMBL30390446 | 0.82 | SLC9A1 (0.40) | KDM4EGLAALDH1A1POLBGAA | |
| SCHEMBL23783264 | 0.81 | CA12 (0.50) | KDM4EALDH1A1POLBHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 219 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466759-A | Preparation method of 2-amino-4-bromo-5-chlorobenzoic acid | 阜新清稷升科技有限公司 | 2024-01-30 | — | — | CN | claimed |
| CN-116854603-A | Preparation method of medical intermediate compound 2-amino-4-bromo-5-chlorobenzoic acid | 沈阳感光化工研究院有限公司 | 2023-10-10 | — | — | CN | claimed |
| CN-110759831-B | Method for preparing halofuginone intermediate 2-amino-4-bromo-5-chlorobenzoic acid | 浙江金伯士药业有限公司 | 2022-09-27 | — | — | CN | claimed |
| CN-112409272-A | Preparation method and application of 6-chloro-7-bromo-4 (3H) -quinazolinone | 河北美荷药业有限公司 | 2021-02-26 | — | — | CN | claimed |
| CN-110759831-A | Method for preparing halofuginone intermediate 2-amino-4-bromo-5-chlorobenzoic acid | 浙江金伯士药业有限公司 | 2020-02-07 | — | — | CN | claimed |
| US-5744638-A | Process for the preparation of haloanthranilic acids | RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) | 1998-04-28 | — | — | US | claimed |
| US-12473291-B2 | Benzodiazepine compound, preparation method therefor, and use thereof in medicine | WEST CHINA HOSPITAL, SICHUAN UNIVERSITY (CN) | 2025-11-18 | — | — | US | disclosed |
| CN-112409272-B | Preparation method and application of 6-chloro-7-bromo-4 (3H) -quinazolinone | 河北美荷药业有限公司 | 2025-09-16 | — | — | CN | disclosed |
| CN-117466759-B | Preparation method of 2-amino-4-bromo-5-chlorobenzoic acid | 阜新清稷升科技有限公司 | 2025-07-25 | — | — | CN | disclosed |
| CN-117466759-B | Preparation method of 2-amino-4-bromo-5-chlorobenzoic acid | 阜新清稷升科技有限公司 | 2025-07-25 | — | — | CN | disclosed |
| US-20250188073-A1 | TRICYCLIC COMPOUNDS AS INHIBITORS OF KRAS | INCYTE CORP (US) | 2025-06-12 | — | — | US | disclosed |
| EP-4548918-A2 | TRICYCLIC COMPOUNDS AS INHIBITORS OF KRAS | Incyte Corporation (US) | 2025-05-07 | — | — | EP | disclosed |
| US-20250122212-A1 | NOVEL COMPOUNDS | SITRYX THERAPEUTICS LIMITED (GB) | 2025-04-17 | — | — | US | disclosed |
| US-5981749-A | Process for producing isatoic anhydrides | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1999-11-09 | — | — | US | disclosed |
| US-5973145-A | Process for producing isatoic anhydrides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-10-26 | — | — | US | disclosed |
| US-5795984-A | Process for producing isatoic anhydrides | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1998-08-18 | — | — | US | disclosed |
| US-5744638-A | Process for the preparation of haloanthranilic acids | RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) | 1998-04-28 | — | — | US | disclosed |
| EP-0781767-A1 | Process for producing isatoic anhydrides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-02 | — | — | EP | disclosed |
| EP-0551632-B1 | Process for the preparation of halogenoanthranilic acid | RIEDEL DE HAEN AG (DE) | 1996-06-26 | — | — | EP | disclosed |
| EP-0551632-A2 | Process for the preparation of halogenoanthranilic acid | RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) | 1993-07-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250188073-A1 | TRICYCLIC COMPOUNDS AS INHIBITORS OF KRAS | KRAS, NRAS, HRAS | KDM4E 4221/4885GLA 1296/4885ALDH1A1 2204/4885 |
| US-20250122212-A1 | NOVEL COMPOUNDS | CYP11B1, CYP11B2, UGT1A1 | KDM4E 3515/4885GLA 1774/4885ALDH1A1 515/4885 |
| US-12473291-B2 | Benzodiazepine compound, preparation method therefor, and use thereof in medicine | GABRA1, GABRA4, GABRR1 | KDM4E 833/4885GLA 4718/4885ALDH1A1 1224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.