Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6479700 | 0.85 | SMN1; SMN2 (0.58) | ALOX15SMN1; SMN2ATMMAPTTP53 | |
| SCHEMBL38664142 | 0.79 | ALOX15 (0.57) | ALOX15SMN1; SMN2ATMMAPTTP53 | |
| SCHEMBL6479789 | 0.79 | SMN1; SMN2 (0.59) | ALOX15SMN1; SMN2ATMMAPTACSS2 | |
| SCHEMBL6493316 | 0.79 | SMN1; SMN2 (0.55) | ALOX15SMN1; SMN2ATMMAPTACSS2 | |
| SCHEMBL10969560 | 0.78 | SMN1; SMN2 (0.57) | ALOX15SMN1; SMN2ATMMAPTTP53 | |
| SCHEMBL22014073 | 0.78 | SMN1; SMN2 (0.51) | ALOX15SMN1; SMN2ATMMAPTTP53 | |
| SCHEMBL8799913 | 0.77 | SMN1; SMN2 (0.60) | ALOX15SMN1; SMN2ATMMAPTTP53 | |
| SCHEMBL30034162 | 0.77 | SMN1; SMN2 (0.55) | ALOX15SMN1; SMN2ATMMAPTTP53 | |
| SCHEMBL5851401 | 0.77 | SMN1; SMN2 (0.55) | ALOX15SMN1; SMN2ATMMAPTTP53 | |
| SCHEMBL13104750 | 0.76 | SMN1; SMN2 (0.52) | ALOX15SMN1; SMN2ATMMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689928-B2 | PREPARED IN SITU FROM A NICKEL, PALLADIUM OR PLATIINUM COMPOUND AND A NITROGEN-CONTAINING LIGAND; OLIGOMERIZING OLEFIN MONOMERS | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2004-02-10 | — | — | US | claimed |
| US-6506859-B1 | Contacting olefinic monomers with activated organoaluminum; addition polymerization | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2003-01-14 | — | — | US | claimed |
| US-20020045790-A1 | Transition metal complexes and oligomers therefrom | EXXONMOBIL CHEMICAL PATENTS INC. | 2002-04-18 | — | — | US | claimed |
| US-6180788-B1 | METAL COMPLEXES FOR CATALYSTS WITH COPPER, SILVER OR GOLD | EXXON RESEARCH AND ENGINEERING COMPANY | 2001-01-30 | — | — | US | claimed |
| US-6777584-B2 | USING ORGANOMETALLIC CATALYST | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2004-08-17 | — | — | US | disclosed |
| US-6689928-B2 | PREPARED IN SITU FROM A NICKEL, PALLADIUM OR PLATIINUM COMPOUND AND A NITROGEN-CONTAINING LIGAND; OLIGOMERIZING OLEFIN MONOMERS | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2004-02-10 | — | — | US | disclosed |
| US-20030166985-A1 | Selective coupling of terminal olefins with ethylene to manufacture linear alpha-olefins | EXXONMOBIL RESEARCH & ENGINEERING COMPANY | 2003-09-04 | — | — | US | disclosed |
| US-6506859-B1 | Contacting olefinic monomers with activated organoaluminum; addition polymerization | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2003-01-14 | — | — | US | disclosed |
| US-20020045790-A1 | Transition metal complexes and oligomers therefrom | EXXONMOBIL CHEMICAL PATENTS INC. | 2002-04-18 | — | — | US | disclosed |
| US-6180788-B1 | METAL COMPLEXES FOR CATALYSTS WITH COPPER, SILVER OR GOLD | EXXON RESEARCH AND ENGINEERING COMPANY | 2001-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030166985-A1 | Selective coupling of terminal olefins with ethylene to manufacture linear alpha-olefins | EEF1D, CYP4Z1, ECH1 | ALOX15 26/4885SMN1; SMN2 3252/4885ATM 4463/4885 |
| US-20020045790-A1 | Transition metal complexes and oligomers therefrom | NCF1, ICOSLG, NPM1 | ALOX15 296/4885SMN1; SMN2 3391/4885ATM 4491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.