Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | TLR4 | O00206 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10401142 | 0.91 | ALDH1A1 (0.41) | ALDH1A1KMT2AKDM4EMEN1MAPT | |
| SCHEMBL1985195 | 0.72 | MEN1 (0.31) | KMT2AMEN1 | |
| SCHEMBL18093460 | 0.69 | ALDH1A1 (0.81) | ALDH1A1KMT2AKDM4EMEN1MAPT | |
| SCHEMBL10517910 | 0.67 | MEN1 (0.36) | ALDH1A1KMT2AKDM4EMEN1MAPT | |
| SCHEMBL25278079 | 0.63 | KDM4E (0.72) | ALDH1A1KMT2AKDM4EMEN1MAPT | |
| SCHEMBL9829912 | 0.63 | ALDH1A1 (0.41) | ALDH1A1KMT2AKDM4EMEN1MAPT | |
| SCHEMBL10903738 | 0.62 | MAPT (0.40) | ALDH1A1KMT2AKDM4EMEN1MAPT | |
| SCHEMBL9834546 | 0.62 | KMT2A (0.49) | ALDH1A1KMT2AKDM4EMEN1MAPT | |
| SCHEMBL8612268 | 0.62 | ALDH1A1 (0.49) | ALDH1A1KMT2AKDM4EMEN1MAPT | |
| SCHEMBL8046948 | 0.62 | ALDH1A1 (0.72) | ALDH1A1KMT2AKDM4EMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5783708-A | HEXAHYDROISOINDOLE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-07-21 | — | — | US | disclosed |