SCHEMBL702495

SCHEMBL702495

c1ccc(O[SiH2]CC(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCN4A P35499 2/20 0.39
HTR2A P28223 5/20 0.39
TAAR1 Q96RJ0 1/20 0.39
HRH1 P35367 5/20 0.37
LTA4H P09960 1/20 0.35
TSHR P16473 1/20 0.35
KCNA3 P22001 1/20 0.34
KDM4E B2RXH2 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
SLC6A4 P31645 1/20 0.34
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
MEN1 O00255 1/20 0.33
OPRM1 P35372 1/20 0.33
OPRD1 P41143 1/20 0.33
KMT2A Q03164 1/20 0.33
CHRNB2 P17787 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15673356 0.87 HTR2A (0.33) SCN4AHTR2ATAAR1HRH1
SCHEMBL705340 0.79 HRH1 (0.43) SCN4AHTR2ATAAR1HRH1SLC6A4
SCHEMBL705544 0.76 HTR2A (0.41) HTR2ATAAR1HRH1TSHRTDP1
SCHEMBL18662231 0.74 HTR2A (0.39) HTR2ATAAR1HRH1TSHRKDM4E
SCHEMBL708761 0.72 HTR2A (0.39) HTR2ATAAR1HRH1TSHRTDP1
SCHEMBL704363 0.72 TAAR1 (0.39) HTR2ATAAR1HRH1TDP1SLC6A4
SCHEMBL706548 0.71 HRH1 (0.39) HTR2ATAAR1HRH1TSHRKDM4E
SCHEMBL707316 0.70 CA4 (0.42) TAAR1LTA4HTSHRKCNA3L3MBTL1
SCHEMBL708012 0.69 HTR2A (0.36) HTR2ATAAR1HRH1TSHRTDP1
SCHEMBL703093 0.68 SCN4A (0.38) SCN4AHTR2ATAAR1LTA4HTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9546237-B2 Stabilization of polymers that contain a hydrolyzable functionality BRIDGESTONE CORPORATION (JP) 2017-01-17 US disclosed
US-20130331520-A1 STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY BRIDGESTONE CORPORATION (JP) 2013-12-12 US disclosed
US-8124239-B2 Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same FUJITSU LIMITED (JP) 2012-02-28 US disclosed
US-20100155121-A1 SILICA FILM FORMING MATERIAL, SILICA FILM AND METHOD OF MANUFACTURING THE SAME, MULTILAYER WIRING STRUCTURE AND METHOD OF MANUFACTURING THE SAME, AND SEMICONDUCTOR DEVICE AND METHOD OF MANUFACTURING THE SAME FUJITSU LIMITED (JP) 2010-06-24 US disclosed
US-7659357-B2 Precursor organosilicon polymer of 1,2-Bis(dimethylethoxysilyl)ethane, 1,4-bis(dimethylethoxysilyl)benzene, tetraethoxysilane, methyltriethoxysilane, phenyltriethoxysilane; dielectric (DE) films having etching/chemical/moisture resistance; adhesion; low DE constant; minimal wiring delay; high speed FUJITSU LIMITED (JP) 2010-02-09 US disclosed
US-20070026689-A1 Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same FUJITSU LIMITED (JP) 2007-02-01 US disclosed