SCHEMBL705340

SCHEMBL705340

c1ccc(O[SiH2]CCC(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 6/20 0.43
HTR2A P28223 6/20 0.41
OPRM1 P35372 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
OPRD1 P41143 1/20 0.38
SCN4A P35499 2/20 0.37
TAAR1 Q96RJ0 1/20 0.37
SLC6A4 P31645 2/20 0.36
KCNH2 Q12809 2/20 0.36
CYP3A4 P08684 2/20 0.36
CYP2D6 P10635 2/20 0.36
CHRM2 P08172 1/20 0.36
HTR1A P08908 1/20 0.36
ADRA2A P08913 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
CHRM1 P11229 1/20 0.36
SMPD1 P17405 1/20 0.36
DRD1 P21728 1/20 0.36
TBXA2R P21731 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL702495 0.79 SCN4A (0.39) HRH1HTR2AOPRM1MEN1KMT2A
SCHEMBL705040 0.78 HRH1 (0.45) HRH1HTR2AOPRM1MEN1KMT2A
SCHEMBL705237 0.74 HRH1 (0.42) HRH1HTR2AOPRM1MEN1KMT2A
SCHEMBL703036 0.74 CYP3A4 (0.43) HRH1HTR2AOPRM1MEN1KMT2A
SCHEMBL705991 0.74 HRH1 (0.50) HRH1HTR2AOPRM1MEN1KMT2A
SCHEMBL713409 0.73 HRH1 (0.41) HRH1HTR2AOPRM1MEN1KMT2A
SCHEMBL705351 0.72 LTA4H (0.41) LMNAHTT
SCHEMBL702334 0.72 HRH1 (0.40) HRH1HTR2AOPRM1MEN1KMT2A
SCHEMBL704483 0.70 HRH1 (0.50) HRH1HTR2AOPRM1MEN1KMT2A
SCHEMBL707328 0.70 HRH1 (0.50) HRH1HTR2AOPRM1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9546237-B2 Stabilization of polymers that contain a hydrolyzable functionality BRIDGESTONE CORPORATION (JP) 2017-01-17 US disclosed
US-20130331520-A1 STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY BRIDGESTONE CORPORATION (JP) 2013-12-12 US disclosed
US-8124239-B2 Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same FUJITSU LIMITED (JP) 2012-02-28 US disclosed
US-20100155121-A1 SILICA FILM FORMING MATERIAL, SILICA FILM AND METHOD OF MANUFACTURING THE SAME, MULTILAYER WIRING STRUCTURE AND METHOD OF MANUFACTURING THE SAME, AND SEMICONDUCTOR DEVICE AND METHOD OF MANUFACTURING THE SAME FUJITSU LIMITED (JP) 2010-06-24 US disclosed
US-7659357-B2 Precursor organosilicon polymer of 1,2-Bis(dimethylethoxysilyl)ethane, 1,4-bis(dimethylethoxysilyl)benzene, tetraethoxysilane, methyltriethoxysilane, phenyltriethoxysilane; dielectric (DE) films having etching/chemical/moisture resistance; adhesion; low DE constant; minimal wiring delay; high speed FUJITSU LIMITED (JP) 2010-02-09 US disclosed
US-20070026689-A1 Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same FUJITSU LIMITED (JP) 2007-02-01 US disclosed