Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | PLAAT3 | P53816 | 3/20 | 0.52 |
| ▸ | PLAAT5 | Q96KN8 | 3/20 | 0.52 |
| ▸ | PLAAT2 | Q9NWW9 | 3/20 | 0.52 |
| ▸ | PLAAT4 | Q9UL19 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | FPR2 | P25090 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ESRRG | P62508 | 1/20 | 0.47 |
| ▸ | VNN1 | O95497 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7026740 | 0.80 | NPC1 (0.51) | NPC1RAB9AGAATAAR1PLAAT3 | |
| SCHEMBL13073347 | 0.76 | KMT2A (0.63) | NPC1RAB9AGAATAAR1PLAAT3 | |
| SCHEMBL16730127 | 0.76 | NPC1 (0.67) | NPC1RAB9AGAATAAR1PLAAT3 | |
| SCHEMBL10692723 | 0.75 | GAA (0.62) | NPC1RAB9AGAATAAR1PLAAT3 | |
| SCHEMBL7705937 | 0.74 | ALDH1A1 (0.76) | NPC1RAB9AGAATAAR1PLAAT3 | |
| Hydrochloric Acid SCHEMBL7032559 | 0.74 | KIF11 (0.46) | ALDH1A1MAPT | |
| SCHEMBL29673846 | 0.73 | SMN1; SMN2 (0.67) | NPC1RAB9AGAATAAR1PLAAT3 | |
| SCHEMBL29673862 | 0.73 | SMN1; SMN2 (0.67) | NPC1RAB9AGAATAAR1PLAAT3 | |
| SCHEMBL7798884 | 0.73 | ALDH1A1 (0.58) | NPC1RAB9AGAATAAR1PLAAT3 | |
| SCHEMBL18603451 | 0.72 | KMT2A (0.69) | NPC1RAB9AGAATAAR1PLAAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002048097-A9 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT OF PARASITIC INFECTIONS | CORVAS INT INC (US) | 2003-05-08 | — | — | WO | disclosed |
| US-20020107266-A1 | Compounds, compositions and methods for treatment of parasitic infections | DENDREON CORPORATION | 2002-08-08 | — | — | US | disclosed |
| WO-2002048097-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT OF PARASITIC INFECTIONS | CORVAS INTERNATIONAL, INC. (US) | 2002-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020107266-A1 | Compounds, compositions and methods for treatment of parasitic infections | CAT, CTSA, CTRL | NPC1 1432/4885RAB9A 1809/4885GAA 72/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.