Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | CTSS | P25774 | 5/20 | 0.55 |
| ▸ | CTSK | P43235 | 4/20 | 0.55 |
| ▸ | CTSL | P07711 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.50 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.50 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.50 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7793390 | 0.88 | KMT2A (0.57) | ALDH1A1CTSSCTSKCTSLKMT2A | |
| SCHEMBL7798889 | 0.87 | NPC1 (0.64) | CTSSCTSKCTSLKMT2ANPC1 | |
| SCHEMBL7799255 | 0.85 | L3MBTL1 (0.50) | CTSLKMT2ANPC1RAB9AGAA | |
| SCHEMBL7798890 | 0.83 | NPC1 (0.48) | ALDH1A1CTSSCTSKCTSLKMT2A | |
| SCHEMBL2247378 | 0.81 | ADAMTS5 (0.59) | ALDH1A1CTSSCTSKCTSLKMT2A | |
| SCHEMBL2247765 | 0.81 | ADAMTS5 (0.59) | ALDH1A1CTSSCTSKCTSLKMT2A | |
| SCHEMBL7705937 | 0.80 | ALDH1A1 (0.76) | ALDH1A1KMT2ANPC1RAB9AGAA | |
| SCHEMBL7793435 | 0.80 | CA12 (0.52) | ALDH1A1CTSSCTSKKMT2ASMN1; SMN2 | |
| SCHEMBL2247441 | 0.78 | CTSS (0.52) | ALDH1A1CTSSCTSKCTSLNPC1 | |
| SCHEMBL5534162 | 0.78 | CTSL (0.58) | CTSSCTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1143960-A2 | CYSTINE DERIVATIVES AS THERAPEUTIC AGENTS FOR MATRIX METALLOPROTEASE RELATED DISEASES | Roche Diagnostics GmbH (DE) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000027378-A2 | CYSTINE DERIVATIVES AS THERAPEUTIC AGENTS FOR MATRIX METALLOPROTEASE RELATED DISEASES | ROCHE DIAGNOSTICS GMBH (DE) | 2000-05-18 | — | — | WO | disclosed |