SCHEMBL70267

SCHEMBL70267

Oc1cccc(Cc2cccc(O)c2)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 1/20 0.65
DRD2 P14416 2/20 0.60
DRD1 P21728 2/20 0.60
TAAR1 Q96RJ0 1/20 0.60
CYP3A4 P08684 2/20 0.58
LMNA P02545 2/20 0.58
CA12 O43570 1/20 0.58
ALDH1A1 P00352 1/20 0.58
CA2 P00918 1/20 0.58
CA5A P35218 1/20 0.58
CA9 Q16790 1/20 0.58
HSD17B10 Q99714 1/20 0.58
CA14 Q9ULX7 1/20 0.58
CA5B Q9Y2D0 1/20 0.58
CYP1A2 P05177 1/20 0.58
PKM P14618 1/20 0.58
ALOX15 P16050 1/20 0.58
NFKB1 P19838 1/20 0.58
MAPK1 P28482 1/20 0.58
KMT2A Q03164 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30979264 1.00 ENPP2 (0.65) ENPP2DRD2DRD1TAAR1CYP3A4
SCHEMBL30471604 0.93 IDH1 (0.59) ENPP2DRD2DRD1TAAR1CYP3A4
SCHEMBL1531575 0.93 IDH1 (0.59) ENPP2DRD2DRD1TAAR1CYP3A4
SCHEMBL921375 0.91 ESR1 (0.64) ENPP2DRD2DRD1TAAR1CYP3A4
SCHEMBL18174858 0.87 ACHE (0.64) ENPP2DRD2DRD1TAAR1CYP3A4
SCHEMBL21005021 0.87 ENPP2 (0.52) ENPP2DRD2DRD1TAAR1CYP3A4
SCHEMBL9221725 0.87 CA2 (0.64) ENPP2DRD2DRD1TAAR1CYP3A4
SCHEMBL13971733 0.85 KMT2A (0.55) ENPP2DRD2DRD1TAAR1CYP3A4
SCHEMBL17243694 0.85 IDH1 (0.51) ENPP2DRD2DRD1TAAR1CYP3A4
SCHEMBL18466196 0.85 ENPP2 (0.50) ENPP2DRD2DRD1TAAR1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 205 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170260389-A1 POLYESTER CO-PHOSPHONATES FRX POLYMERS, INC. 2017-09-14 US claimed
EP-2867272-A1 POLYESTER CO-PHOSPHONATES FRX Polymers, Inc. (US) 2015-05-06 EP claimed
WO-2014005136-A1 POLYESTER CO-PHOSPHONATES FRX POLYMERS, INC. (US) 2014-01-03 WO claimed
US-20140000751-A1 POLYESTER CO-PHOSPHONATES DOSKOCIL MANUFACTURING COMPANY, INC. 2014-01-02 US claimed
US-4910233-A Using aromatic polymer having methylene connecting groups THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1990-03-20 US claimed
EP-0220080-B1 COMPOSITIONS BASED ON PHTHALONITRILE-TERMINATED POLYARYLOXY PYRIDINE OLIGOMERS, THEIR PREPARATION, THEIR USE IN THE PREPARATION OF POLYARYLOXY PYRIDINE COPHTHALOCYANINE LATTICES AND LATTICES OBTAINED CENTRE D'ETUDE DES MATERIAUX ORGANIQUES POUR TECHNOLOGIES AVANCEES (FR) 1990-02-07 EP claimed
US-RE32745-E Polymeric resins derived from 1-oxa-3-aza tetraline group-containing compounds and cycloaliphatic epoxides GURIT-ESSEX AG (CH) 1988-09-06 US claimed
US-4764578-A Compositions of polyaryloxypyridine oligomers with phthalonitrile end groups, their preparation and use for manufacturing polyaryloxypyridine co-phthalocyanine lattices CENTRE D'ETUDE DES MATERIAUX ORGANIQUES POUR TECHNOLOGIES AVANCEES (FR) 1988-08-16 US claimed
US-4607091-A Polymeric resins derived from 1-oxa-3-aza tetraline group-containing compounds and cycloaliphatic epoxides GURIT-ESSEX AG (CH) 1986-08-19 US claimed
US-4071484-A POLYETHERURETHANE COPOLYMER KOHKOKU CHEMICAL INDUSTRY CO., LTD. (JA) 1978-01-31 US claimed
CN-110914383-B Liquid crystal polymer shell material 离子材料第二公司 2024-03-08 CN disclosed
US-20240052093-A1 CURABLE RESIN, CURABLE RESIN COMPOSITION, AND CURED PRODUCT DIC CORPORATION (JP) 2024-02-15 US disclosed
EP-4318574-A1 RESIN COMPOSITION, CURED PRODUCT SHEET, COMPOSITE MOLDED BODY AND SEMICONDUCTOR DEVICE Mitsubishi Chemical Corporation (JP) 2024-02-07 EP disclosed
US-20240010814-A1 RESIN COMPOSITION, CURED PRODUCT SHEET, COMPOSITE MOLDED BODY, AND SEMICONDUCTOR DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2024-01-11 US disclosed
US-11866635-B2 Thermosetting material and cured product SEKISUI CHEMICAL CO., LTD. (JP) 2024-01-09 US disclosed
US-4320144-A Fungicidal use of diphenyl esters of alkylenes GAF CORPORATION (US) 1982-03-16 US disclosed
US-4101323-A Radiation-sensitive copying composition HOECHST AKTIENGESELLSCHAFT (DE) 1978-07-18 US disclosed
US-4071484-A POLYETHERURETHANE COPOLYMER KOHKOKU CHEMICAL INDUSTRY CO., LTD. (JA) 1978-01-31 US disclosed
US-4064086-A SPIROLACTONES NATIONAL PATENT DEVELOPMENT CORPORATION (US) 1977-12-20 US disclosed
US-3936482-A Organo tin compounds useful as catalysts in the polycondensation of organosilicon compounds RHONE-POULENC, S.A. (FR) 1976-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170260389-A1 POLYESTER CO-PHOSPHONATES PHOSPHO1, PNKP, PHYKPL ENPP2 518/4885DRD2 4728/4885DRD1 4719/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.