Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.64 |
| ▸ | IDH1 | O75874 | 2/20 | 0.53 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 2/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70267 | 0.87 | ENPP2 (0.65) | IDH1ENPP2CHRM2CHRM1CHRM3 | |
| SCHEMBL30979264 | 0.87 | ENPP2 (0.65) | IDH1ENPP2CHRM2CHRM1CHRM3 | |
| SCHEMBL29459538 | 0.87 | TAAR1 (0.60) | ACHEIDO1TAAR1MAPK1DAO | |
| SCHEMBL30000562 | 0.87 | TAAR1 (0.60) | ACHEIDO1TAAR1MAPK1DAO | |
| SCHEMBL1263547 | 0.87 | TAAR1 (0.60) | ACHEIDO1TAAR1MAPK1DAO | |
| SCHEMBL17243694 | 0.86 | IDH1 (0.51) | ACHEIDH1ENPP2CHRM2CHRM1 | |
| SCHEMBL6288838 | 0.86 | ESR1 (0.56) | ACHEIDH1IDO1TAAR1CYP1A2 | |
| SCHEMBL6400232 | 0.83 | ALOX5 (0.49) | ACHEIDO1TAAR1CYP1A2CYP3A4 | |
| SCHEMBL8093804 | 0.82 | TAAR1 (0.56) | ACHEIDH1IDO1TAAR1DAO | |
| SCHEMBL26300969 | 0.81 | ACHE (0.55) | ACHEENPP2IDO1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11518766-B2 | Tricyclic compound, preparation method therefor and use thereof | SHANGHAI JEMINCARE PHARMACEUTICALS CO., LTD. (CN) | 2022-12-06 | — | — | US | disclosed |
| US-9477148-B1 | Polymer, method for preparing the same, and a photosensitive resin composition thereof | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2016-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11518766-B2 | Tricyclic compound, preparation method therefor and use thereof | TFPI, TFPI2, F11 | ACHE 1761/4885IDH1 3254/4885ENPP2 213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.