Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | AGXT | P21549 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5968623 | 0.79 | TSHR (0.43) | TSHRIDO1AGXTALDH1A1SLC6A2 | |
| SCHEMBL703504 | 0.79 | CA1 (0.40) | IDO1ALDH1A1SLC6A2TAAR1TDP1 | |
| SCHEMBL18297928 | 0.78 | TSHR (0.41) | TSHRIDO1AGXTALDH1A1SLC6A2 | |
| SCHEMBL707650 | 0.76 | IDO1 (0.50) | IDO1L3MBTL1LMNA | |
| SCHEMBL18297931 | 0.75 | TSHR (0.43) | TSHRIDO1AGXTALDH1A1SLC6A2 | |
| SCHEMBL18297901 | 0.75 | TSHR (0.43) | TSHRIDO1AGXTALDH1A1SLC6A2 | |
| SCHEMBL703823 | 0.75 | IDO1 (0.44) | IDO1TDP1L3MBTL1MAOB | |
| SCHEMBL106501 | 0.75 | TSHR (0.52) | TSHRIDO1AGXTALDH1A1SLC6A2 | |
| SCHEMBL18297893 | 0.75 | TSHR (0.52) | TSHRIDO1AGXTALDH1A1SLC6A2 | |
| SCHEMBL2959136 | 0.74 | TSHR (0.57) | TSHRIDO1AGXTALDH1A1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210363164-A1 | Hydroxide-Catalyzed Formation Of Silicon-Oxygen Bonds By Dehydrogenative Coupling Of Hydrosilanes And Alcohols | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2021-11-25 | — | — | US | disclosed |
| EP-3328922-B1 | HYDROXIDE-CATALYZED FORMATION OF SILICON-OXYGEN BONDS BY DEHYDROGENATIVE COUPLING OF HYDROSILANES AND ALCOHOLS | CALIFORNIA INST OF TECHN (US) | 2021-09-08 | — | — | EP | disclosed |
| EP-3865491-A1 | SILYL ETHERS AS PRODUCTS OF THE HYDROXIDE-CATALYZED FORMATION OF SILICON-OXYGEN BONDS BY DEHYDROGENATIVE COUPLING OF HYDROSILANES AND ALCOHOLS | California Institute of Technology (US) | 2021-08-18 | — | — | EP | disclosed |
| CN-112480162-A | Hydroxide catalyzed formation of silicon-oxygen bonds by dehydrocoupling of hydrosilanes and alcohols | 加州理工学院 | 2021-03-12 | — | — | CN | disclosed |
| CN-107849279-B | Hydroxide catalyzed formation of silicon-oxygen bonds by dehydrocoupling of hydrosilanes and alcohols | 加州理工学院 | 2020-12-01 | — | — | CN | disclosed |
| US-20190241587-A1 | Hydroxide-Catalyzed Formation Of Silicon-Oxygen Bonds By Dehydrogenative Coupling Of Hydrosilanes And Alcohols | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2019-08-08 | — | — | US | disclosed |
| US-10259831-B2 | Hydroxide-catalyzed formation of silicon-oxygen bonds by dehydrogenative coupling of hydrosilanes and alcohols | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2019-04-16 | — | — | US | disclosed |
| CN-107849279-A | Hydroxide catalyzed formation of silicon-oxygen bonds by dehydrocoupling of hydrosilanes and alcohols | 加州理工学院 | 2018-03-27 | — | — | CN | disclosed |
| US-20170029447-A1 | HYDROXIDE-CATALYZED FORMATION OF SILICON-OXYGEN BONDS BY DEHYDROGENATIVE COUPLING OF HYDROSILANES AND ALCOHOLS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2017-02-02 | — | — | US | disclosed |
| US-20170029447-A1 | HYDROXIDE-CATALYZED FORMATION OF SILICON-OXYGEN BONDS BY DEHYDROGENATIVE COUPLING OF HYDROSILANES AND ALCOHOLS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2017-02-02 | — | — | US | disclosed |
| US-8124239-B2 | Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same | FUJITSU LIMITED (JP) | 2012-02-28 | — | — | US | disclosed |
| US-20100155121-A1 | SILICA FILM FORMING MATERIAL, SILICA FILM AND METHOD OF MANUFACTURING THE SAME, MULTILAYER WIRING STRUCTURE AND METHOD OF MANUFACTURING THE SAME, AND SEMICONDUCTOR DEVICE AND METHOD OF MANUFACTURING THE SAME | FUJITSU LIMITED (JP) | 2010-06-24 | — | — | US | disclosed |
| US-7659357-B2 | Precursor organosilicon polymer of 1,2-Bis(dimethylethoxysilyl)ethane, 1,4-bis(dimethylethoxysilyl)benzene, tetraethoxysilane, methyltriethoxysilane, phenyltriethoxysilane; dielectric (DE) films having etching/chemical/moisture resistance; adhesion; low DE constant; minimal wiring delay; high speed | FUJITSU LIMITED (JP) | 2010-02-09 | — | — | US | disclosed |
| US-20070026689-A1 | Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same | FUJITSU LIMITED (JP) | 2007-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210363164-A1 | Hydroxide-Catalyzed Formation Of Silicon-Oxygen Bonds By Dehydrogenative Coupling Of Hydrosilanes And Alcohols | SORD, ADH1A, ADH1C | TSHR 4752/4885IDO1 2584/4885AGXT 2677/4885 |
| US-10259831-B2 | Hydroxide-catalyzed formation of silicon-oxygen bonds by dehydrogenative coupling of hydrosilanes and alcohols | SORD, ADH1A, ADH1C | TSHR 4752/4885IDO1 2584/4885AGXT 2677/4885 |
| US-20170029447-A1 | HYDROXIDE-CATALYZED FORMATION OF SILICON-OXYGEN BONDS BY DEHYDROGENATIVE COUPLING OF HYDROSILANES AND ALCOHOLS | SORD, ADH1A, ADH1C | TSHR 4752/4885IDO1 2584/4885AGXT 2677/4885 |
| US-20190241587-A1 | Hydroxide-Catalyzed Formation Of Silicon-Oxygen Bonds By Dehydrogenative Coupling Of Hydrosilanes And Alcohols | SORD, ADH1A, ADH1C | TSHR 4752/4885IDO1 2584/4885AGXT 2677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.