Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28201210 | 0.86 | TSHR (0.58) | POLBADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL9331896 | 0.86 | PKM (0.58) | POLBADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL8443576 | 0.81 | ADRA1D (0.56) | POLBADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL6936789 | 0.80 | ALDH1A1 (0.58) | POLBALDH1A1TSHRLMNAMEN1 | |
| Hydrochloric Acid SCHEMBL7029028 | 0.78 | POLB (0.55) | POLBADRA1DADRA1AADRA1BALDH1A1 | |
| Hydrochloric Acid SCHEMBL6706983 | 0.78 | ALDH1A1 (0.63) | POLBALDH1A1TSHRLMNAMEN1 | |
| Hydrochloric Acid SCHEMBL6706985 | 0.78 | ALDH1A1 (0.63) | POLBALDH1A1TSHRLMNAMEN1 | |
| SCHEMBL11509122 | 0.78 | GAA (0.61) | POLBADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL8492185 | 0.77 | DRD2 (0.52) | POLBALDH1A1TSHRLMNAMEN1 | |
| Hydrochloric Acid SCHEMBL11817434 | 0.77 | GAA (0.60) | POLBADRA1DADRA1AADRA1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1276731-A2 | BRANCHED ADAMANTYL AND NORADAMANTYL ARYL- AND ARALKYLPIPERAZINES WITH SEROTONIN 5-HT 1A ACTIVITY | Wyeth (US) | 2003-01-22 | — | — | EP | claimed |
| WO-2001034586-A2 | BRANCHED ADAMANTYL AND NORADAMANTYL ARYL- AND ARALKYLPIPERAZINES WITH SEROTONIN 5-HT1A ACTIVITY | WYETH (US) | 2001-05-17 | — | — | WO | claimed |