SCHEMBL702950

SCHEMBL702950

COc1cc(C)ccc1CNC(=O)C(=O)NCCc1ccc(C)cn1

nearest known ligand 0.81

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 3/20 0.81
TAS1R1 Q7RTX1 3/20 0.81
ALDH1A1 P00352 6/20 0.49
LMNA P02545 2/20 0.46
POLB P06746 2/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
TSHR P16473 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
F2 P00734 1/20 0.43
THRB P10828 1/20 0.42
PDE10A Q9Y233 1/20 0.41
NPC1 O15118 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30777573 1.00 TAS1R3 (0.81) TAS1R3TAS1R1ALDH1A1LMNAPOLB
SCHEMBL18971254 0.93 TAS1R3 (0.71) TAS1R3TAS1R1ALDH1A1LMNAPOLB
SCHEMBL701192 0.92 TAS1R3 (0.86) TAS1R3TAS1R1ALDH1A1LMNAPOLB
SCHEMBL18971636 0.91 TAS1R3 (0.69) TAS1R3TAS1R1ALDH1A1LMNAPOLB
SCHEMBL19494332 0.91 TAS1R3 (0.69) TAS1R3TAS1R1ALDH1A1LMNAPOLB
Hydrochloric Acid SCHEMBL4257386 0.91 TAS1R3 (0.85) TAS1R3TAS1R1ALDH1A1LMNAPOLB
SCHEMBL701975 0.90 TAS1R3 (1.00) TAS1R3TAS1R1ALDH1A1LMNAPOLB
SCHEMBL30557690 0.87 TAS1R3 (0.64) TAS1R3TAS1R1ALDH1A1LMNAPOLB
SCHEMBL701181 0.87 TAS1R3 (0.64) TAS1R3TAS1R1ALDH1A1LMNAPOLB
SCHEMBL14052196 0.87 TAS1R3 (0.63) TAS1R3TAS1R1ALDH1A1LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118175935-A Composition and food for enhancing spicy taste 味之素株式会社 2024-06-11 CN claimed
CN-116058486-A Spicy enhancer composition and food 味之素株式会社 2023-05-05 CN claimed
WO-2023074853-A1 COMPOSITION FOR ENHANCING SPICY FLAVOR AND FOOD AJINOMOTO CO., INC. (JP) 2023-05-04 WO claimed
EP-3431464-A2 NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF Senomyx Inc. (US) 2019-01-23 EP claimed
EP-3235811-B1 PROCESS OF PREPARING OXALAMIDES SENOMYX INC (US) 2018-07-25 EP claimed
EP-3235811-A1 PROCESS OF PREPARING OXALAMIDES Senomyx, Inc. (US) 2017-10-25 EP claimed
EP-2742983-B1 Method for isolating fragrance and flavour compounds SYMRISE AG (DE) 2017-08-23 EP claimed
US-9144248-B2 Cinnamamides as savory flavorings SYMRISE AG (DE) 2015-09-29 US claimed
EP-2742983-A1 Method for isolating fragrance and flavour compounds Symrise AG (DE) 2014-06-18 EP claimed
EP-2529632-B1 Cinnamic acid amides as spicy flavour agents SYMRISE AG (DE) 2013-08-28 EP claimed
US-20120308703-A1 Cinnamamides as savory flavorings SYMRISE AG (DE) 2012-12-06 US claimed
EP-2529632-A1 Cinnamic acid amides as spicy flavour agents Symrise AG (DE) 2012-12-05 EP claimed
US-8148536-B2 Comestible compositions comprising high potency savory flavorants, and processes for producing them SENOMYX, INC. (US) 2012-04-03 US claimed
US-8124121-B2 Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof SENOMYX, INC. (US) 2012-02-28 US claimed
US-20090111834-A1 NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF SENOMYX, INC. 2009-04-30 US claimed
EP-2010009-A2 COMESTIBLE COMPOSITIONS COMPRISING HIGH POTENCY SAVORY FLAVORANTS, AND PROCESSES FOR PRODUCING THEM Senomyx, Inc. (US) 2009-01-07 EP claimed
WO-2007124152-A2 COMESTIBLE COMPOSITIONS COMPRISING HIGH POTENCY SAVORY FLAVORANTS, AND PROCESSES FOR PRODUCING THEM SENOMYX, INC. (US) 2007-11-01 WO claimed
US-20050084506-A1 Amide compounds such as (R)-methyl 2-(3-chloro-4-methoxybenzamido)-4-methylpentanoate and urea compounds such as 1-(2-chlorophenyl)-3-(heptan-4-yl)urea for modulating taste of food or drug products FIRMENICH INCORPORATED 2005-04-21 US claimed
EP-3911172-B1 COMBINATION OF SATIETY COMPONENTS WITH ARGININE SYMRISE AG (DE) 2026-04-15 EP disclosed
WO-2005041684-A2 NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF SENOMYX INC. (US) 2005-05-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090111834-A1 NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF TAS1R2, TAS1R1, TAS2R30 TAS1R3 5/4885TAS1R1 2/4885ALDH1A1 1089/4885
US-20050084506-A1 Amide compounds such as (R)-methyl 2-(3-chloro-4-methoxybenzamido)-4-methylpentanoate and urea compounds such as 1-(2-chlorophenyl)-3-(heptan-4-yl)urea for modulating taste of food or drug products TAS2R40, TAS2R4, TAS2R30 TAS1R3 17/4885TAS1R1 11/4885ALDH1A1 1936/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.