Sugi Predict

Sugi Predict / Compounds / SCHEMBL701181

SCHEMBL701181

SCHEMBL701181

COc1cc(C)ccc1CNC(=O)C(=O)NCCc1ccccn1

nearest known ligand 0.64

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ TAS1R3 Q7RTX0 4/20 0.64
▸ TAS1R1 Q7RTX1 4/20 0.64
▸ PKM P14618 2/20 0.53
▸ F2 P00734 1/20 0.52
▸ RAB9A P51151 5/20 0.51
▸ NPC1 O15118 4/20 0.51
▸ MEN1 O00255 1/20 0.49
▸ LMNA P02545 1/20 0.49
▸ POLB P06746 1/20 0.49
▸ KMT2A Q03164 1/20 0.49
▸ SMN1; SMN2 Q16637 3/20 0.49
▸ ALDH1A1 P00352 3/20 0.48
▸ HTT P42858 1/20 0.47
▸ MAPK1 P28482 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30557690 1.00 TAS1R3 (0.64) TAS1R3TAS1R1PKMF2RAB9A
SCHEMBL30645001 0.89 TAS1R3 (0.64) TAS1R3TAS1R1PKMRAB9ANPC1
SCHEMBL30064606 0.89 TAS1R3 (0.64) TAS1R3TAS1R1PKMRAB9ANPC1
SCHEMBL702030 0.89 TAS1R3 (0.64) TAS1R3TAS1R1PKMRAB9ANPC1
SCHEMBL31627278 0.89 TAS1R3 (0.62) TAS1R3TAS1R1PKMF2MEN1
SCHEMBL701814 0.88 TAS1R3 (0.77) TAS1R3TAS1R1RAB9ANPC1MEN1
SCHEMBL702950 0.87 TAS1R3 (0.81) TAS1R3TAS1R1F2NPC1MEN1
SCHEMBL30777573 0.87 TAS1R3 (0.81) TAS1R3TAS1R1F2NPC1MEN1
SCHEMBL704790 0.86 TAS1R3 (0.59) TAS1R3TAS1R1RAB9ANPC1SMN1; SMN2
SCHEMBL702807 0.86 TAS1R3 (0.74) TAS1R3TAS1R1RAB9ANPC1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 281 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118175935-A Composition and food for enhancing spicy taste 味之素株式会社 2024-06-11 — — CN claimed
CN-116058486-A Spicy enhancer composition and food 味之素株式会社 2023-05-05 — — CN claimed
WO-2023074853-A1 COMPOSITION FOR ENHANCING SPICY FLAVOR AND FOOD AJINOMOTO CO., INC. (JP) 2023-05-04 — — WO claimed
EP-3431464-A2 NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF Senomyx Inc. (US) 2019-01-23 — — EP claimed
EP-2742983-B1 Method for isolating fragrance and flavour compounds SYMRISE AG (DE) 2017-08-23 — — EP claimed
US-9144248-B2 Cinnamamides as savory flavorings SYMRISE AG (DE) 2015-09-29 — — US claimed
EP-2742983-A1 Method for isolating fragrance and flavour compounds Symrise AG (DE) 2014-06-18 — — EP claimed
EP-2529632-B1 Cinnamic acid amides as spicy flavour agents SYMRISE AG (DE) 2013-08-28 — — EP claimed
US-20120308703-A1 Cinnamamides as savory flavorings SYMRISE AG (DE) 2012-12-06 — — US claimed
EP-2529632-A1 Cinnamic acid amides as spicy flavour agents Symrise AG (DE) 2012-12-05 — — EP claimed
US-8124121-B2 Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof SENOMYX, INC. (US) 2012-02-28 — — US claimed
US-20090111834-A1 NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF SENOMYX, INC. 2009-04-30 — — US claimed
US-20050084506-A1 Amide compounds such as (R)-methyl 2-(3-chloro-4-methoxybenzamido)-4-methylpentanoate and urea compounds such as 1-(2-chlorophenyl)-3-(heptan-4-yl)urea for modulating taste of food or drug products FIRMENICH INCORPORATED 2005-04-21 — — US claimed
US-20260114489-A1 DRY PARTICLE COATING TO PRODUCE STABLE POWDERS GIVAUDAN SA (CH) 2026-04-30 — — US disclosed
EP-3911172-B1 COMBINATION OF SATIETY COMPONENTS WITH ARGININE SYMRISE AG (DE) 2026-04-15 — — EP disclosed
EP-4637391-A2 DRY PARTICLE COATING TO PRODUCE STABLE POWDERS Givaudan SA (CH) 2025-10-29 — — EP disclosed
EP-1659881-A2 NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF Senomyx Inc. (US) 2006-05-31 — — EP disclosed
US-20060045953-A1 Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers SENOMYX, INC. 2006-03-02 — — US disclosed
WO-2005041684-A2 NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF SENOMYX INC. (US) 2005-05-12 — — WO disclosed
US-20050084506-A1 Amide compounds such as (R)-methyl 2-(3-chloro-4-methoxybenzamido)-4-methylpentanoate and urea compounds such as 1-(2-chlorophenyl)-3-(heptan-4-yl)urea for modulating taste of food or drug products FIRMENICH INCORPORATED 2005-04-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090111834-A1 NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF TAS1R2, TAS1R1, TAS2R30 TAS1R3 5/4885TAS1R1 2/4885PKM 2463/4885
US-20050084506-A1 Amide compounds such as (R)-methyl 2-(3-chloro-4-methoxybenzamido)-4-methylpentanoate and urea compounds such as 1-(2-chlorophenyl)-3-(heptan-4-yl)urea for modulating taste of food or drug products TAS2R40, TAS2R4, TAS2R30 TAS1R3 17/4885TAS1R1 11/4885PKM 2257/4885
US-20260114489-A1 DRY PARTICLE COATING TO PRODUCE STABLE POWDERS LIPA, DAGLA, SCD TAS1R3 1417/4885TAS1R1 2150/4885PKM 1600/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.