Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7025989 | 0.92 | THRA (0.49) | THRBTHRA | |
| SCHEMBL8800887 | 0.83 | THRA (0.62) | THRBTHRA | |
| SCHEMBL7025061 | 0.81 | THRA (0.60) | THRBTHRA | |
| SCHEMBL8799562 | 0.78 | THRA (0.69) | THRBTHRA | |
| SCHEMBL6656178 | 0.77 | THRA (0.55) | THRBTHRA | |
| SCHEMBL6665930 | 0.76 | THRA (0.56) | THRBTHRA | |
| SCHEMBL7058206 | 0.76 | THRB (0.47) | THRBTHRA | |
| SCHEMBL23863357 | 0.75 | THRB (0.52) | THRBTHRA | |
| SCHEMBL7058208 | 0.75 | THRB (0.44) | THRBTHRA | |
| SCHEMBL1643216 | 0.75 | THRA (0.57) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307426-A1 | AMINO DIPHENYL ETHERS AND AMIDO DIPHENYL ETHERS | Bayer Aktiengesellschaft (DE) | 2003-05-07 | — | — | EP | disclosed |
| US-6555580-B2 | Treating arteriosclerosis and hypercholesterolaemia | BAYER AKTIENGESELLSCHAFT (DE) | 2003-04-29 | — | — | US | disclosed |
| US-20030027862-A1 | Amino-and amido-diphenyl ethers | BAYER AKTIENGESELLSCHAFT (DE) | 2003-02-06 | — | — | US | disclosed |
| WO-2002012169-A1 | AMINO DIPHENYL ETHERS AND AMIDO DIPHENYL ETHERS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-02-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030027862-A1 | Amino-and amido-diphenyl ethers | APOB, DAO, DNPEP | THRB 1856/4885THRA 2763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.