SCHEMBL7029656

SCHEMBL7029656

O=[N+]([O-])c1cc2scnc2cc1Cl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 1/20 0.43
LMNA P02545 1/20 0.41
TSHR P16473 1/20 0.41
MAPK1 P28482 1/20 0.41
ALDH1A1 P00352 3/20 0.40
CYP3A4 P08684 1/20 0.40
VCAM1 P19320 4/20 0.39
MAPT P10636 2/20 0.37
EGFR P00533 1/20 0.36
KDM4E B2RXH2 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
HKDC1 Q2TB90 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
PDE7A Q13946 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
ATIC P31939 1/20 0.35
STIM1 Q13586 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11593638 0.86 LMNA (0.42) LMNATSHRALDH1A1CYP3A4MAPT
SCHEMBL31359248 0.80 GAA (0.55) TSHRMAPK1ALDH1A1CYP3A4MAPT
SCHEMBL22655746 0.77 ALDH1A1 (0.36) LMNAMAPK1ALDH1A1CYP3A4MAPT
SCHEMBL6142347 0.77 GAA (0.48) LMNATSHRMAPK1ALDH1A1CYP3A4
SCHEMBL29414890 0.76 ALDH1A1 (0.43) ALDH1A1MAPTKDM4ENPC1RAB9A
SCHEMBL7597205 0.76 ALDH1A1 (0.43) ALDH1A1MAPTKDM4ENPC1RAB9A
4-Chloro-3-Nitrobenzoic Acid SCHEMBL6640805 0.74 VCAM1 (0.52) LMNATSHRMAPK1ALDH1A1VCAM1
SCHEMBL7825439 0.73 PGK1 (0.53) PGK1LMNATSHRMAPK1ALDH1A1
SCHEMBL7222197 0.72 MAPT (0.44) LMNAALDH1A1CYP3A4MAPTKDM4E
SCHEMBL14973435 0.72 PTPN11 (0.57) PGK1LMNATSHRMAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1291714-A1 An aqueous thermally bleachable composition useful in a photothermographic element EASTMAN KODAK COMPANY (US) 2003-03-12 EP disclosed
EP-1288709-A1 A thermally bleachable dye for a color photothermographic element EASTMAN KODAK COMPANY (US) 2003-03-05 EP disclosed
US-6492076-B1 UNDERGOES CHANGE IN ELECTROMAGNETIC ABSORPTION WHEN HEATED; ANTIHALATION OR FILTER LAYERS CONTAINING ZWITTERIONIC 1-AMINOPYRIDINIUM DYE EASTMAN KODAK COMPANY 2002-12-10 US disclosed
US-6451516-B1 AMINOPYRIDINIUM DYE WITH METHIN LINKAGE TERMINATED BY A HETEROCVYCLIC NUCLEUS AS FOUND IN CYANINE DYES EASTMAN KODAK COMPANY 2002-09-17 US disclosed
EP-0383092-B1 Chromogenic merocyanine enzyme substrates BAYER AG (US) 1995-12-13 EP disclosed
EP-0296873-B1 DIRECT POSITIVE DIMETHINE CYANINE DYES CONTAINING 1-ARYL-2-HETEROARYL INDOLE NUCLEUS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-09-08 EP disclosed
US-5191073-A Indicators for colorimetric analysis of enzymes MILES INC. (US) 1993-03-02 US disclosed
US-5187049-A Spectral sensitizing dye and salt formed from leuco dye and oxidizing acid MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-02-16 US disclosed
US-5153104-A Negative-acting photothermographic imaging systems comprising also a nitrate, an initiator, a leuco dye and a binder; colorfastness; clean background MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-10-06 US disclosed
US-5153105-A Mixture with nitrate salt, leuco dye and binder MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-10-06 US disclosed
US-4075017-A Photothermographic material containing a combination of energy-sensitive organic dyes and process of forming a positive or negative image with the material EASTMAN KODAK COMPANY (US) 1978-02-21 US disclosed
US-4066403-A DECOMPOSITION, PERMEABLE BARRIERS EASTMAN KODAK COMPANY (US) 1978-01-03 US disclosed
US-4035190-A 2-ISOXAZOLIN-3-HETEROCYCLIC-SUBSTITUTED MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1977-07-12 US disclosed
US-4028113-A Photographic supports and elements utilizing photobleachable O-nitroarylidene dyes EASTMAN KODAK COMPANY (US) 1977-06-07 US disclosed
US-4025347-A Fogged direct-positive silver halide emulsion containing a cyanine dye having an indole or indolenine nucleus substituted with a benzoyl or a phenylsulfonyl group MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1977-05-24 US disclosed
US-RE29168-E HEAT SENSITIVE, ANTIHALATION LAYER EASTMAN KODAK COMPANY (US) 1977-04-05 US disclosed
US-3988154-A Photographic supports and elements utilizing photobleachable omicron-nitroarylidene dyes EASTMAN KODAK COMPANY (US) 1976-10-26 US disclosed
US-3988156-A Photographic supports and elements utilizing photobleachable o-nitroarylidene dyes EASTMAN KODAK COMPANY (US) 1976-10-26 US disclosed
US-3984248-A Photographic polymeric film supports containing photobleachable o-nitroarylidene dyes EASTMAN KODAK COMPANY (US) 1976-10-05 US disclosed
US-3955996-A Method for spectrally sensitizing photographic light-sensitive emulsion FUJI PHOTO FILM CO., LTD. (JA) 1976-05-11 US disclosed