Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10983286 | 0.94 | — | — | |
| SCHEMBL5154615 | 0.63 | — | — | |
| SCHEMBL279134 | 0.63 | — | — | |
| SCHEMBL826939 | 0.60 | — | — | |
| SCHEMBL24579379 | 0.59 | ALAD (0.39) | — | |
| SCHEMBL15113561 | 0.58 | MAPK14 (0.36) | — | |
| SCHEMBL6384656 | 0.58 | — | — | |
| SCHEMBL23491386 | 0.58 | — | — | |
| SCHEMBL544996 | 0.58 | — | — | |
| SCHEMBL31311129 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6646165-B2 | Reacting halothiophenol compound with an alkali metal hydroxide to obtain an alkali metal halothiophenolate compound; oxidizing in the presence of a mineral acid to produce bishalophenyl disulfide | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2003-11-11 | — | — | US | disclosed |
| US-20030060665-A1 | Process for producing bishalophenyl disulfide | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2003-03-27 | — | — | US | disclosed |
| EP-1277731-A1 | PROCESS FOR PRODUCING BISHALOPHENYL DISULFIDE | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2003-01-22 | — | — | EP | disclosed |
| EP-0151529-B1 | 5-(AMINO OR SUBSTITUTED AMINO)-1,2,3-TRIAZOLES | MERCK & CO. INC. (US) | 1991-09-18 | — | — | EP | disclosed |
| US-4590201-A | ANTICOCCIDIAL AGENT FOR ANIMALS PARTICULARLY FOR POULTRY | MERCK & CO., INC. (US) | 1986-05-20 | — | — | US | disclosed |
| EP-0151529-A2 | 5-(Amino or substituted amino)-1,2,3-triazoles | MERCK & CO. INC. (US) | 1985-08-14 | — | — | EP | disclosed |