Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1889392 | 0.84 | ALDH1A1 (0.46) | AKR1C3GAAMAPTALDH1A1HPGD | |
| SCHEMBL1122739 | 0.82 | BCL2 (0.64) | AKR1C3BCL2MCL1GAAMAPT | |
| SCHEMBL1882897 | 0.79 | ALDH1A1 (0.41) | MAPTGABRA1ALDH1A1LMNANPSR1 | |
| SCHEMBL13387766 | 0.79 | AKR1C3 (0.53) | AKR1C3BCL2MCL1GAAMAPT | |
| SCHEMBL11218987 | 0.78 | TSHR (0.52) | AKR1C3BCL2MCL1GAAMAPT | |
| SCHEMBL3355855 | 0.77 | PTGS2 (0.57) | AKR1C3BCL2MCL1GAAMAPT | |
| SCHEMBL4144845 | 0.77 | PTGS2 (0.57) | AKR1C3BCL2MCL1GAAMAPT | |
| SCHEMBL11490665 | 0.77 | LMNA (0.53) | MAPTALDH1A1LMNAHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10590134 | 0.77 | TSHR (0.50) | AKR1C3BCL2MCL1GAAMAPT | |
| SCHEMBL28456033 | 0.76 | LMNA (0.46) | AKR1C3MAPTALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030049807-A1 | Micro-organism possessing enantioselective and regioselective nitrile hydratase/amidase activities | INSTITUTO BIOCHIMICO ITALIANO GIOVANNI LOREZINI S.P.A. (IT) | 2003-03-13 | — | — | US | disclosed |
| EP-1291435-A2 | A micro-organism possessing enantioselective and regioselective nitrile hydratase/amidase activities | ISTITUTO BIOCHIMICO ITALIANO GIOVANNI LORENZINI S.p.A. (IT) | 2003-03-12 | — | — | EP | disclosed |