Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.58 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.58 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.52 |
| ▸ | TTR | P02766 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10885499 | 0.84 | CRHBP (0.76) | CRHBPCRHR2GPR35TTRKDM4E | |
| SCHEMBL2078816 | 0.83 | TTR (0.57) | CRHBPCRHR2GPR35TTRKDM4E | |
| SCHEMBL429752 | 0.82 | GPR35 (0.71) | GPR35TTRKDM4EMEN1ALDH1A1 | |
| SCHEMBL11740610 | 0.80 | GPR35 (0.48) | GPR35TTRKDM4EMEN1ALDH1A1 | |
| SCHEMBL29674743 | 0.80 | ERN1 (0.59) | GPR35TTRKDM4EMEN1ALDH1A1 | |
| SCHEMBL1943304 | 0.80 | GPR35 (0.74) | GPR35TTRKDM4EMEN1ALDH1A1 | |
| SCHEMBL752254 | 0.80 | ERN1 (0.59) | GPR35TTRKDM4EMEN1ALDH1A1 | |
| SCHEMBL18304977 | 0.80 | TTR (0.54) | GPR35TTRKDM4EMEN1ALDH1A1 | |
| SCHEMBL8229963 | 0.79 | ERN1 (0.67) | CRHBPCRHR2GPR35TTRKDM4E | |
| SCHEMBL7026296 | 0.79 | TTR (0.47) | GPR35TTRKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6608233-B2 | Nitrating a bis(4-hydroxyphenyl) bonded to each other or through an electron-donating bridging group, sulfoxide, sulfone or carbonyl group using nitric acid in a solvent and free from other acids | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2003-08-19 | — | — | US | disclosed |
| US-20030055288-A1 | Process for producting bis(4-hydroxy-3-nitrophenyl) compound | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2003-03-20 | — | — | US | disclosed |
| EP-1277727-A1 | PROCESS FOR PRODUCING BIS(4-HYDROXY-3-NITROPHENYL) COMPOUND | Nippon Kayaku Kabushiki Kaisha (JP) | 2003-01-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055288-A1 | Process for producting bis(4-hydroxy-3-nitrophenyl) compound | NOS3, NOS2, NOS1 | CRHBP 3061/4885CRHR2 4709/4885GPR35 3425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.