SCHEMBL23701252

SCHEMBL23701252

FC(CCO[SiH3])(c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
ALDH1A1 P00352 2/20 0.41
KIF11 P52732 4/20 0.35
PTPN1 P18031 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA5A P35218 1/20 0.32
CA9 Q16790 1/20 0.32
MAPK1 P28482 1/20 0.32
LTA4H P09960 1/20 0.32
KCNN4 O15554 1/20 0.31
CYP1A2 P05177 1/20 0.30
TAAR1 Q96RJ0 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23701213 0.79 TSHR (0.41) TSHRALDH1A1KIF11MAPK1KCNN4
SCHEMBL703111 0.78 KIF11 (0.48) KIF11MAPK1
SCHEMBL707648 0.72 MAPK1 (0.39) ALDH1A1KIF11MAPK1KCNN4TAAR1
SCHEMBL706645 0.72 KCNN4 (0.35) TSHRALDH1A1KIF11MAPK1KCNN4
SCHEMBL27491062 0.71 TSHR (0.46) TSHRALDH1A1KIF11PTPN1CA1
SCHEMBL705749 0.71 KIF11 (0.55) KIF11
SCHEMBL702618 0.71 RIPK1 (0.35) ALDH1A1KIF11MAPK1KCNN4CYP1A2
SCHEMBL708503 0.71 SCN1A (0.37) TSHRALDH1A1KIF11MAPK1LTA4H
SCHEMBL9402727 0.71 ALDH1A1 (0.33) TSHRALDH1A1KIF11
SCHEMBL3481507 0.71 ESR1 (0.46) TSHRMAPK1KCNN4CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11807758-B2 Siloxane polymer and method of producing siloxane polymer JNC CORPORATION (JP) 2023-11-07 US disclosed
US-20210238419-A1 SILOXANE POLYMER AND METHOD OF PRODUCING SILOXANE POLYMER JNC CORPORATION (JP) 2021-08-05 US disclosed