Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | GCGR | P47871 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7036422 | 0.92 | CRHR1 (0.33) | CRHR1SMN1; SMN2SYK | |
| SCHEMBL7031378 | 0.90 | HSD11B1 (0.37) | NPC1TSHRRAB9ASMN1; SMN2 | |
| SCHEMBL29287776 | 0.90 | PSMB5 (0.34) | — | |
| SCHEMBL7033012 | 0.89 | EDNRB (0.32) | — | |
| SCHEMBL7037024 | 0.89 | HSD11B1 (0.34) | NPC1TSHRRAB9ASMN1; SMN2 | |
| SCHEMBL7034550 | 0.87 | SYK (0.33) | CRHR1ADORA3NPC1RAB9ASYK | |
| SCHEMBL7031849 | 0.87 | HSD11B1 (0.37) | ADORA3TSHRRAB9ASMN1; SMN2 | |
| SCHEMBL7036050 | 0.87 | UCHL3 (0.34) | — | |
| SCHEMBL7039419 | 0.87 | NPC1 (0.32) | ADORA3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7037707 | 0.86 | HSD11B1 (0.36) | NPC1TSHRRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620953-B1 | Complexing dimethylbis(2-methyl-4,5-benzoindenyl)silane with transition metal compounds such as 2,4-di-tert-butylphenoxide, zirconium monochloride, to form polymerization catalysts | BASSELL POLYOLEFINE GMBH (DE) | 2003-09-16 | — | — | US | disclosed |
| EP-1133504-B1 | METHOD FOR PRODUCING MONOARYLOXY-ANSA-METALLOCENES | BASELL POLYOLEFINE GMBH (DE) | 2003-03-12 | — | — | EP | disclosed |