Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL3 | P15374 | 2/20 | 0.34 |
| ▸ | CASR | P41180 | 2/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.30 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7036418 | 0.93 | BRD4 (0.31) | CASR | |
| SCHEMBL7039603 | 0.91 | NR3C1 (0.30) | — | |
| SCHEMBL7031437 | 0.88 | BRD4 (0.32) | CASR | |
| SCHEMBL7031378 | 0.87 | HSD11B1 (0.37) | — | |
| SCHEMBL7031827 | 0.87 | CRHR1 (0.32) | — | |
| SCHEMBL29287776 | 0.87 | PSMB5 (0.34) | — | |
| SCHEMBL7037024 | 0.86 | HSD11B1 (0.34) | — | |
| SCHEMBL7033012 | 0.86 | EDNRB (0.32) | — | |
| SCHEMBL7196903 | 0.84 | BRD4 (0.31) | — | |
| SCHEMBL7039419 | 0.84 | NPC1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620953-B1 | Complexing dimethylbis(2-methyl-4,5-benzoindenyl)silane with transition metal compounds such as 2,4-di-tert-butylphenoxide, zirconium monochloride, to form polymerization catalysts | BASSELL POLYOLEFINE GMBH (DE) | 2003-09-16 | — | — | US | disclosed |
| EP-1133504-B1 | METHOD FOR PRODUCING MONOARYLOXY-ANSA-METALLOCENES | BASELL POLYOLEFINE GMBH (DE) | 2003-03-12 | — | — | EP | disclosed |