Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7036422 | 0.89 | CRHR1 (0.33) | SYKCRHR1ENPP1ALDH1A1 | |
| SCHEMBL7038530 | 0.89 | EDNRB (0.35) | — | |
| SCHEMBL5836913 | 0.89 | ADRB2 (0.33) | — | |
| SCHEMBL3400108 | 0.88 | TSHR (0.32) | — | |
| SCHEMBL7031827 | 0.87 | CRHR1 (0.32) | SYKCRHR1ADORA3NPC1RAB9A | |
| SCHEMBL7196862 | 0.85 | SMN1; SMN2 (0.34) | NPC1ALDH1A1RAB9A | |
| SCHEMBL7201450 | 0.85 | SYK (0.31) | SYK | |
| SCHEMBL7031437 | 0.85 | BRD4 (0.32) | MAPT | |
| SCHEMBL7036446 | 0.85 | S1PR1 (0.32) | NPC1MAPTRAB9A | |
| SCHEMBL7034874 | 0.83 | HSD11B1 (0.39) | NPC1ALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620953-B1 | Complexing dimethylbis(2-methyl-4,5-benzoindenyl)silane with transition metal compounds such as 2,4-di-tert-butylphenoxide, zirconium monochloride, to form polymerization catalysts | BASSELL POLYOLEFINE GMBH (DE) | 2003-09-16 | — | — | US | disclosed |
| EP-1133504-B1 | METHOD FOR PRODUCING MONOARYLOXY-ANSA-METALLOCENES | BASELL POLYOLEFINE GMBH (DE) | 2003-03-12 | — | — | EP | disclosed |