Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 6/20 | 0.46 |
| ▸ | CHRM3 known ✓ | P20309 | 6/20 | 0.46 |
| ▸ | CHRM2 known ✓ | P08172 | 5/20 | 0.43 |
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.43 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11025015 | 0.90 | CHRM5 (0.38) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL6986829 | 0.88 | KDM4E (0.43) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL27571208 | 0.87 | ACHE (0.42) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL61004 | 0.87 | ACHE (0.42) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL1201070 | 0.86 | ACHE (0.41) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL25422694 | 0.86 | ACHE (0.43) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL33607 | 0.86 | ACHE (0.43) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL9135367 | 0.86 | BBOX1 (0.40) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL19406439 | 0.85 | CHRM5 (0.42) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL28176347 | 0.84 | ACHE (0.39) | CHRM5CHRM1CHRM3CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1283077-A1 | Obtaining a Lotus effect by preventing microbial growth on self-cleaning surfaces | Creavis Gesellschaft für Technologie und Innovation mbH (DE) | 2003-02-12 | — | — | EP | disclosed |