Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESRRG | P62508 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 2/20 | 0.35 |
| ▸ | KLK1 | P06870 | 2/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6290435 | 0.81 | EGFR (0.34) | DEGS1KDRESR1ESR2PLG | |
| SCHEMBL6290421 | 0.81 | EGFR (0.34) | DEGS1KDRESR1ESR2PLG | |
| SCHEMBL7032353 | 0.74 | FNTA (0.46) | RAB9ANPC1DEGS1KDRPOLB | |
| Trifluoroacetic Acid SCHEMBL6286326 | 0.74 | NR1H4 (0.37) | RAB9ANPC1DEGS1KMT2AMEN1 | |
| SCHEMBL7037687 | 0.72 | CCR5 (0.39) | NPC1MMP1MMP2MMP9ESRRG | |
| Hydrochloric Acid SCHEMBL6290557 | 0.70 | FLT3 (0.39) | RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL7209538 | 0.69 | BACE1 (0.40) | MMP1MMP2MMP9PLGKLK1 | |
| Hydrochloric Acid SCHEMBL6290419 | 0.69 | DHPS (0.43) | RAB9ANPC1KMT2AMEN1CASP3 | |
| Trifluoroacetic Acid SCHEMBL7038495 | 0.69 | TP53 (0.35) | RAB9ANPC1KLK1NLRP3TP53 | |
| Trifluoroacetic Acid SCHEMBL6287884 | 0.66 | KEAP1 (0.37) | RAB9ANPC1POLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1291341-A1 | COMPOUNDS EXHIBITING THROMBOPOIETIN-LIKE ACTIVITIES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-03-12 | — | — | EP | disclosed |