Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.36 |
| ▸ | CA1 | P00915 | 5/20 | 0.36 |
| ▸ | CA2 | P00918 | 5/20 | 0.36 |
| ▸ | CA9 | Q16790 | 5/20 | 0.36 |
| ▸ | COMT | P21964 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 4/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7028654 | 0.86 | CA2 (0.44) | CA12CA1CA2CA9COMT | |
| SCHEMBL7031174 | 0.85 | COMT (0.36) | CA12CA1CA2CA9COMT | |
| SCHEMBL7030429 | 0.85 | ALDH1A1 (0.38) | CA12CA1CA2CA9COMT | |
| SCHEMBL7031980 | 0.84 | COMT (0.35) | CA12CA1CA2CA9COMT | |
| SCHEMBL7029041 | 0.83 | KDM4E (0.44) | LMNAKDM4EPOLBMAPT | |
| SCHEMBL7029160 | 0.82 | PRKCI (0.38) | CA12CA1CA2CA9COMT | |
| SCHEMBL7023383 | 0.82 | MAPK8 (0.34) | CA12CA1CA2CA9COMT | |
| SCHEMBL7029060 | 0.81 | LMNA (0.33) | CA12CA1CA2CA9COMT | |
| SCHEMBL7027264 | 0.80 | ADORA2B (0.34) | CA12CA1CA2CA9COMT | |
| SCHEMBL8559545 | 0.79 | CA12 (0.34) | CA12CA1CA2CA9COMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1232505-C | Substituted sulfonamido (thio) carbonyl compounds | BAYER AG (DE) | 2005-12-21 | — | — | CN | disclosed |
| CN-1439631-A | Substituted sulfonamido (thio) carbonyl compounds | BAYER AG (DE) | 2003-09-03 | — | — | CN | disclosed |
| US-20030162979-A1 | Substituted sulphonylamino(thio)carbonyl compounds | MULLER KLAUS-HELMUT (DE) | 2003-08-28 | — | — | US | disclosed |
| CN-1105717-C | Substituted sulfonamido (thio) carbonyl compounds | BAYER AG (DE) | 2003-04-16 | — | — | CN | disclosed |
| US-6441195-B1 | 2-ALKOXYCARBONYL-3-SULPHONAMIDE, SULPHONYL ISOCYANATE OR SULPHONYL ISOTHIOCYANATE-THIOPHENES; PRE- OR POSTEMERGENCE HERBICIDES; EFFICIENCY | BAYER AKTIENGESELLSCHAFT (DE) | 2002-08-27 | — | — | US | disclosed |
| EP-0859774-B1 | SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES | BAYER AG (DE) | 2002-04-03 | — | — | EP | disclosed |
| US-6180567-B1 | REACTING 2-ALKOXYCARBONYL-BENZENESULFONAMIDE DERIVATIVE WITH 1,2,4-(1H)TRIAZOLE-5-(THI)ONE DERIVATIVE | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-30 | — | — | US | disclosed |
| CN-1207099-A | Substituted sulfonamido (thio) carbonyl compounds | BAYER AG (DE) | 1999-02-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162979-A1 | Substituted sulphonylamino(thio)carbonyl compounds | CBR3, CTH, CBR1 | CA12 1571/4885CA1 1037/4885CA2 248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.