Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.36 |
| ▸ | PI4KA | P42356 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28871077 | 0.83 | ALDH1A1 (0.47) | PRKCIMAPTKDM4ERAD52ALDH1A1 | |
| SCHEMBL3071570 | 0.76 | PRKCI (0.41) | PRKCIMAPTKDM4ERAD52ALDH1A1 | |
| SCHEMBL7028875 | 0.76 | PRKCI (0.41) | PRKCIMAPTKDM4ERAD52ALDH1A1 | |
| SCHEMBL7090538 | 0.76 | PRKCI (0.41) | PRKCIMAPTKDM4ERAD52ALDH1A1 | |
| SCHEMBL7035006 | 0.76 | PRKCI (0.41) | PRKCIMAPTKDM4ERAD52ALDH1A1 | |
| SCHEMBL28272777 | 0.76 | PRKCI (0.41) | PRKCIMAPTKDM4ERAD52ALDH1A1 | |
| SCHEMBL29149388 | 0.73 | MMP12 (0.47) | MAPTKDM4EALDH1A1RAB9AMEN1 | |
| SCHEMBL24533998 | 0.72 | ULK1 (0.39) | PRKCIMAPTKDM4ERAD52ALDH1A1 | |
| SCHEMBL7093035 | 0.72 | ELANE (0.39) | PRKCIMAPTKDM4ERAD52ALDH1A1 | |
| SCHEMBL2915006 | 0.72 | PRKCI (0.38) | PRKCIMAPTKDM4ERAD52ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118879219-A | Light pink anti-pollution car cover film | 中建材玻璃新材料研究院集团有限公司 | 2024-11-01 | — | — | CN | claimed |
| CN-118879219-A | Light pink anti-pollution car cover film | 中建材玻璃新材料研究院集团有限公司 | 2024-11-01 | — | — | CN | disclosed |
| US-8778937-B2 | Benzimidazole boronic acid derivatives as PI3 kinase inhibitors | GLAXOSMITHKLINE LLC (US) | 2014-07-15 | — | — | US | disclosed |
| US-20130157977-A1 | Benzimidazole Boronic Acid Derivatives As PI3 Kinase Inhibitors | GLAXOSMITHKLINE LLC (US) | 2013-06-20 | — | — | US | disclosed |
| US-20030181730-A1 | Novel benzimidazole derivatives | SYNAPTIC PHARMACEUTICAL CORPORATION | 2003-09-25 | — | — | US | disclosed |
| US-20030022927-A1 | Novel benzimidazole derivatives | SYNAPTIC PHARMACEUTICAL CORPORATION | 2003-01-30 | — | — | US | disclosed |
| US-6495583-B1 | DRUG FOR TREATING AN ALPHA-2 ADRENERGIC RECEPTOR ASSOCIATED DISORDER, NASAL CONGENSTION AND ALLEVIATING PAIN | SYNAPTIC PHARMACEUTICAL CORPORATION | 2002-12-17 | — | — | US | disclosed |
| US-6436982-B1 | USEFUL AS ANALGESIC, SEDATIVE OR ANAESTHETIC AGENTS | SYNAPTIC PHARMACEUTICAL CORPORATION | 2002-08-20 | — | — | US | disclosed |
| US-20020072536-A1 | Novel benzimidazole derivatives | SYNAPTIC PHARMACEUTICAL CORPORATION | 2002-06-13 | — | — | US | disclosed |
| US-6403626-B1 | USEFUL AS ANALGESIC, SEDATIVE OR ANAESTHETIC AGENTS | SYNAPTIC PHARMACEUTICAL CORPORATION | 2002-06-11 | — | — | US | disclosed |
| US-20020065307-A1 | Novel benzimidazole derivatives | SYNAPTIC PHARMACEUTICAL CORPORATION | 2002-05-30 | — | — | US | disclosed |
| US-6316637-B1 | SELECTIVE FOR CLONED HUMAN ALPHA 2 RECEPTORS AND ARE USEFUL AS ANALGESIC, SEDATIVE OR ANAESTHETIC AGENTS | SYNAPTIC PHARMACEUTICAL CORPORATION | 2001-11-13 | — | — | US | disclosed |
| EP-0775134-A4 | NOVEL BENZIMIDAZOLE DERIVATIVES | SYNAPTIC PHARMA CORP (US) | 1997-08-13 | — | — | EP | disclosed |
| EP-0775134-A1 | Imidazolin-2-ylaminobenzimidazole derivatives | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996004270-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1996-02-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020065307-A1 | Novel benzimidazole derivatives | OPRD1, OPRL1, OPRM1 | PRKCI 2441/4885MAPT 4094/4885KDM4E 1828/4885 |
| US-20020072536-A1 | Novel benzimidazole derivatives | OPRD1, OPRL1, OPRM1 | PRKCI 2310/4885MAPT 4095/4885KDM4E 1775/4885 |
| US-20030022927-A1 | Novel benzimidazole derivatives | OPRL1, OPRD1, OPRM1 | PRKCI 2446/4885MAPT 4207/4885KDM4E 2083/4885 |
| US-20030181730-A1 | Novel benzimidazole derivatives | OPRD1, OPRL1, OPRM1 | PRKCI 2441/4885MAPT 4094/4885KDM4E 1828/4885 |
| US-20130157977-A1 | Benzimidazole Boronic Acid Derivatives As PI3 Kinase Inhibitors | PI4KB, PI4KA, PIK3CB | PRKCI 64/4885MAPT 3226/4885KDM4E 3876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.