Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | BRD4 | O60885 | 2/20 | 0.50 |
| ▸ | METAP2 | P50579 | 2/20 | 0.50 |
| ▸ | MPI | P34949 | 1/20 | 0.50 |
| ▸ | METAP1 | P53582 | 1/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29856077 | 0.79 | KDM4E (0.54) | KDM4EL3MBTL1HSP90AA1HTTLMNA | |
| SCHEMBL10110908 | 0.78 | HTR1A (0.43) | KDM4EHSP90AA1HTTLMNAMAPT | |
| SCHEMBL17931872 | 0.75 | COMT (0.55) | KDM4EL3MBTL1HSP90AA1HTTLMNA | |
| SCHEMBL1920452 | 0.73 | KDM4E (0.70) | KDM4EL3MBTL1HSP90AA1HTTLMNA | |
| Methane SCHEMBL27551425 | 0.72 | KDM4E (0.68) | KDM4EL3MBTL1HSP90AA1HTTLMNA | |
| SCHEMBL27816447 | 0.72 | KDM4E (0.68) | KDM4EL3MBTL1HSP90AA1HTTLMNA | |
| SCHEMBL12600031 | 0.71 | KDM4E (0.61) | KDM4EL3MBTL1HSP90AA1HTTLMNA | |
| Methane SCHEMBL28088738 | 0.70 | KDM4E (0.66) | KDM4EL3MBTL1HSP90AA1HTTLMNA | |
| SCHEMBL31481274 | 0.70 | KDM4E (0.74) | KDM4EL3MBTL1HSP90AA1HTTLMNA | |
| SCHEMBL30503296 | 0.69 | ALDH1A1 (0.38) | KDM4EL3MBTL1HSP90AA1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124368-B2 | Fluorogenic protein kinase substrates | Life Technologies Corporation (US) | 2012-02-28 | — | — | US | disclosed |
| US-8124368-B2 | Fluorogenic protein kinase substrates | Life Technologies Corporation (US) | 2012-02-28 | — | — | US | disclosed |
| US-8124368-B2 | Fluorogenic protein kinase substrates | Life Technologies Corporation (US) | 2012-02-28 | — | — | US | disclosed |
| EP-2063915-A1 | FLUOROGENIC PROTEIN KINASE SUBSTRATES | Invitrogen Corporation (US) | 2009-06-03 | — | — | EP | disclosed |
| WO-2008016762-A1 | FLUOROGENIC PROTEIN KINASE SUBSTRATES | INVITROGEN CORPORATION (US) | 2008-02-07 | — | — | WO | disclosed |
| WO-2008016762-A1 | FLUOROGENIC PROTEIN KINASE SUBSTRATES | INVITROGEN CORPORATION (US) | 2008-02-07 | — | — | WO | disclosed |
| US-20080009026-A1 | FLUOROGENIC PROTEIN KINASE SUBSTRATES | INVITROGEN CORPORATION (US) | 2008-01-10 | — | — | US | disclosed |
| US-20080009026-A1 | FLUOROGENIC PROTEIN KINASE SUBSTRATES | INVITROGEN CORPORATION (US) | 2008-01-10 | — | — | US | disclosed |
| US-20080009026-A1 | FLUOROGENIC PROTEIN KINASE SUBSTRATES | INVITROGEN CORPORATION (US) | 2008-01-10 | — | — | US | disclosed |