SCHEMBL30503296

SCHEMBL30503296

Oc1cccnc1C1OCCO1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
COMT P21964 2/20 0.38
METAP2 P50579 2/20 0.38
METAP1 P53582 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
MMP2 P08253 1/20 0.38
CHRM1 P11229 1/20 0.38
TSHR P16473 1/20 0.38
ADRA1A P35348 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
NSD2 O96028 1/20 0.36
CASP6 P55212 1/20 0.36
CYP2C19 P33261 1/20 0.34
HIF1A Q16665 1/20 0.34
KDM4E B2RXH2 6/20 0.33
ALOX12 P18054 1/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
HTT P42858 2/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17796068 0.77 NSD2 (0.36) ALDH1A1NSD2CASP6KDM4EHTT
SCHEMBL1991557 0.77 CASP6 (0.50) ALDH1A1NSD2CASP6CYP2C19HIF1A
SCHEMBL2645775 0.74 COMT (0.42) ALDH1A1COMTMETAP2METAP1L3MBTL1
SCHEMBL21505363 0.73 TRIM24 (0.46) ALDH1A1L3MBTL1TSHRNSD2CASP6
SCHEMBL6983787 0.73 NSD2 (0.34) ALDH1A1NSD2CASP6
SCHEMBL28666083 0.73 DRD2 (0.50)
SCHEMBL16060505 0.73 MMP2 (0.38) ALDH1A1COMTMETAP2METAP1L3MBTL1
SCHEMBL1990688 0.70 CYP1A2 (0.49) ALDH1A1L3MBTL1CYP2C19KDM4ENPC1
SCHEMBL703334 0.69 KDM4E (0.50) ALDH1A1COMTMETAP2METAP1L3MBTL1
SCHEMBL8761755 0.69 CYP11B2 (0.43) ALDH1A1COMTMETAP2METAP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116472267-A Butyrylcholinesterase reactivating agent 法兰西国由中央军队卫生服务局代表 2023-07-21 CN disclosed