Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PDE4A | P27815 | 3/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27196389 | 0.81 | HTR1A (0.47) | HTR1AADRA1DADRA1AADRA1BKMT2A | |
| SCHEMBL703334 | 0.78 | KDM4E (0.50) | KMT2APDE4DKDM4EALDH1A1GAA | |
| SCHEMBL1506959 | 0.76 | HTR1A (0.53) | HTR1AADRA1DADRA1AADRA1BKMT2A | |
| SCHEMBL3693025 | 0.75 | HTR1A (0.51) | HTR1AADRA1DADRA1AADRA1BKMT2A | |
| SCHEMBL12600028 | 0.75 | HTR1A (0.53) | HTR1AADRA1DADRA1AADRA1BKMT2A | |
| SCHEMBL9028027 | 0.74 | MAOA (0.42) | HTR1AADRA1DADRA1AADRA1BKMT2A | |
| SCHEMBL30297578 | 0.74 | HTR1A (0.39) | HTR1AADRA1DADRA1AADRA1BKMT2A | |
| SCHEMBL9026884 | 0.72 | PDE4D (0.46) | HTR1AADRA1DADRA1AADRA1BKMT2A | |
| SCHEMBL3147583 | 0.72 | PSMD14 (0.58) | HTR1AADRA1DADRA1AADRA1BKMT2A | |
| SCHEMBL9186410 | 0.70 | KMT2A (0.55) | HTR1AADRA1DADRA1AADRA1BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124368-B2 | Fluorogenic protein kinase substrates | Life Technologies Corporation (US) | 2012-02-28 | — | — | US | disclosed |
| US-8124368-B2 | Fluorogenic protein kinase substrates | Life Technologies Corporation (US) | 2012-02-28 | — | — | US | disclosed |
| WO-2008016762-A1 | FLUOROGENIC PROTEIN KINASE SUBSTRATES | INVITROGEN CORPORATION (US) | 2008-02-07 | — | — | WO | disclosed |
| US-20080009026-A1 | FLUOROGENIC PROTEIN KINASE SUBSTRATES | INVITROGEN CORPORATION (US) | 2008-01-10 | — | — | US | disclosed |
| US-20080009026-A1 | FLUOROGENIC PROTEIN KINASE SUBSTRATES | INVITROGEN CORPORATION (US) | 2008-01-10 | — | — | US | disclosed |