Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | BRAF | P15056 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL697433 | 0.86 | NPC1 (0.44) | KMT2ANPC1RAB9AMEN1KDM4E | |
| SCHEMBL697919 | 0.86 | NPC1 (0.44) | KMT2ANPC1RAB9ATSHRMAOB | |
| SCHEMBL27845585 | 0.83 | KMT2A (0.37) | KMT2ANPC1RAB9ABRAFKDM4E | |
| SCHEMBL697991 | 0.83 | CYP1A2 (0.41) | KMT2ANPC1RAB9ABRAFKDM4E | |
| SCHEMBL696226 | 0.79 | KMT2A (0.41) | KMT2ANPC1RAB9AMEN1KDM4E | |
| SCHEMBL705111 | 0.76 | KMT2A (0.48) | KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL712135 | 0.75 | NPC1 (0.65) | KMT2ANPC1RAB9ATSHRBRAF | |
| SCHEMBL10957602 | 0.74 | CA12 (0.38) | KMT2ANPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL11137294 | 0.74 | NPC1 (0.42) | KMT2ANPC1RAB9AMEN1KDM4E | |
| SCHEMBL697784 | 0.74 | MTOR (0.47) | KMT2ANPC1RAB9AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | disclosed |