Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | BACE1 | P56817 | 3/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | FPR1 | P21462 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ATP4A | P20648 | 1/20 | 0.44 |
| ▸ | ATP4B | P51164 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11281941 | 0.82 | HTR7 (0.58) | HTR7ALDH1A1SMN1; SMN2MAPK1HDAC4 | |
| SCHEMBL26009120 | 0.79 | ACHE (0.57) | BACE1ACHELMNAMAPTALDH1A1 | |
| SCHEMBL16236644 | 0.79 | KDM4E (0.53) | BACE1AKR1C3AKR1C2LMNAMAPT | |
| SCHEMBL8584051 | 0.78 | BACE1 (0.57) | BACE1LMNAMAPTALDH1A1TUBB4A | |
| SCHEMBL7037049 | 0.78 | GAPDH (0.52) | HTR7BACE1ACHELMNAMAPT | |
| SCHEMBL19685841 | 0.77 | CYP3A4 (0.46) | BACE1ACHEPKMLMNAMAPT | |
| SCHEMBL6901954 | 0.76 | PPARG (0.54) | BACE1ACHEPKMLMNAMAPT | |
| SCHEMBL180340 | 0.76 | PPARG (0.47) | BACE1ACHEPKMMAPTALDH1A1 | |
| SCHEMBL3326684 | 0.76 | ACHE (0.53) | BACE1ACHELMNAMAPTALDH1A1 | |
| SCHEMBL19084240 | 0.76 | BACE1 (0.56) | BACE1ACHELMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758243-B1 | BINDING OF E-SELECTIN, P-SELECTIN OR L-SELECTIN TO SIALYL-LEWISx OR SIALYL-LEWISa | TEXAS BIOTECHNOLOGY CORP (US) | 2003-03-12 | — | — | EP | disclosed |