Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.32 |
| ▸ | CDK2 | P24941 | 4/20 | 0.32 |
| ▸ | CDK7 | P50613 | 4/20 | 0.32 |
| ▸ | CCNH | P51946 | 4/20 | 0.32 |
| ▸ | MNAT1 | P51948 | 4/20 | 0.32 |
| ▸ | CCNK | O75909 | 3/20 | 0.32 |
| ▸ | CDK12 | Q9NYV4 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28565830 | 0.83 | TLR8 (0.37) | TLR8KDM4ECYP1A2FDPSALDH1A1 | |
| SCHEMBL5675046 | 0.69 | FGFR4 (0.45) | KDM4ECYP1A2CCNA2CDK2CDK7 | |
| SCHEMBL6669910 | 0.68 | CYP2D6 (0.38) | KDM4EALDH1A1RAB9AMAPTSLC6A2 | |
| SCHEMBL277885 | 0.68 | ESR1 (0.41) | KDM4ECYP1A2ALDH1A1ATMRAB9A | |
| SCHEMBL12003727 | 0.67 | CYP1A2 (0.56) | KDM4ECYP1A2ALDH1A1HPGDMAPT | |
| SCHEMBL31391395 | 0.67 | CYP1A2 (0.56) | KDM4ECYP1A2ALDH1A1HPGDMAPT | |
| SCHEMBL1573639 | 0.67 | ALDH1A1 (0.41) | KDM4EALDH1A1HPGDATMMAPT | |
| SCHEMBL27864952 | 0.66 | ALDH1A1 (0.35) | TLR8KDM4ECCNA2CDK2CDK7 | |
| SCHEMBL983301 | 0.65 | KDM4E (0.38) | TLR8KDM4ECYP1A2FDPSALDH1A1 | |
| SCHEMBL23978672 | 0.64 | CYP1A2 (0.45) | TLR8KDM4ECYP1A2RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040053923-A1 | Novel isoindole derivatives | BANYU PHARMACEUTICAL CO., LTD. | 2004-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053923-A1 | Novel isoindole derivatives | GPR119, SLC5A2, SLC5A1 | TLR8 2191/4885KDM4E 1370/4885CYP1A2 68/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.