SCHEMBL7035819

SCHEMBL7035819

C=Cc1ccc(C)cc1[SiH](Cl)Cl

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
NQO2 P16083 1/20 0.32
ALDH1A1 P00352 2/20 0.32
GABRA1 P14867 1/20 0.32
GABRG2 P18507 1/20 0.32
GABRB3 P28472 1/20 0.32
LMNA P02545 1/20 0.32
CYP1A2 P05177 3/20 0.31
CYP2A6 P11509 2/20 0.31
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8760067 0.77 TP53 (0.34) TP53TDP1NQO2
SCHEMBL7036482 0.74 TDP1 (0.36) TP53TDP1NQO2ALDH1A1LMNA
SCHEMBL5084622 0.73 TDP1 (0.44) TP53TDP1NQO2ALDH1A1LMNA
SCHEMBL139560 0.72 GABRA1 (0.50) TP53TDP1NQO2ALDH1A1GABRA1
SCHEMBL14926 0.72 AMY1A (0.44) TP53TDP1NQO2ALDH1A1LMNA
SCHEMBL29354308 0.72 AMY1A (0.44) TP53TDP1NQO2ALDH1A1LMNA
Water SCHEMBL23457130 0.70 AMY1A (0.43) TP53TDP1NQO2ALDH1A1GABRA1
SCHEMBL388507 0.70 ALDH1A1 (0.50) TDP1ALDH1A1LMNA
SCHEMBL9253034 0.68 ALDH1A1 (0.48) TP53TDP1NQO2ALDH1A1GABRA1
SCHEMBL2992480 0.68 TDP1 (0.52) TP53TDP1NQO2ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0811628-B1 METHYLALUMINO-OXY COMPOUNDS AND CATALYSTS FOR THE PREPARATION O POLYMERS CONTAINING THE SAME IDEMITSU PETROCHEMICAL CO (JP) 2003-03-05 EP disclosed
US-6277934-B1 A SYNDIOTACTIC HOMO- OR COPOLYMER FROM A STYRENIC COMPOUND IN THE PRESENCE OF A METALLOCENE OF HIGH, STABLE ACTIVITY COMPRISING A TITANIUM COMPOUND AND AN ORGANIC ALUMINOXY COMPOUND OF SPECIFIC NUCLEAR MAGNETIC RESONANCE SPECTRUM IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2001-08-21 US disclosed
EP-0737694-B1 PROCESS FOR PRODUCING OLEFIN POLYMER AND ETHYLENE POLYMER IDEMITSU KOSAN CO (JP) 2001-06-06 EP disclosed
US-6034191-A Organic aluminoxy compound and catalyst for producing polymer IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2000-03-07 US disclosed
US-5917073-A Organic aluminoxy compound and catalyst for producing polymer IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1999-06-29 US disclosed
US-5739225-A CATALYTIC HOMO- OR COPOLYMERIZATION IN PRESENCE OF A MIXTURE COMPRISING A TRANSITION METAL COMPOUND AND AN ALUMOXANE IDEMITSU KOSAN CO., LTD. (JP) 1998-04-14 US disclosed
EP-0811628-A1 ORGANIC ALUMINO-OXY COMPOUNDS AND CATALYSTS FOR THE PREPARATION O POLYMERS CONTAINING THE SAME IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1997-12-10 EP disclosed
EP-0570932-B1 Styrenic block copolymer and process for producing same IDEMITSU KOSAN CO (JP) 1997-07-23 EP disclosed
EP-0559108-B1 Graft copolymer, process for production thereof and resin composition containing same IDEMITSU KOSAN CO (JP) 1997-05-28 EP disclosed
EP-0505997-B1 Process for producing styrenic polymer and copolymer IDEMITSU KOSAN CO (JP) 1997-05-28 EP disclosed
US-5391626-A Syndiotactic, high performance, compatibility and adhesiveness; molding materials IDEMITSU KOSAN CO., LTD. (JP) 1995-02-21 US disclosed
US-5378777-A Styrene monomer substituted with silicon group, transition metal complex catalyst IDEMITSU KOSAN CO., LTD. (JP) 1995-01-03 US disclosed
US-5362814-A Styrene polymers with olefin monomers and diolefin monomers for impact strength in molding materials IDEMITSU KOSAN CO., LTD. (JP) 1994-11-08 US disclosed
EP-0570931-A2 Styrenic polymer, process for producing same and multi-layer material comprising same IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-11-24 EP disclosed
EP-0570932-A2 Styrenic block copolymer and process for producing same IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-11-24 EP disclosed
US-5250629-A Graft polymerization of styrene and ethylenically unsaturated monomer using transition metal catalysts, organoaluminum compounds; films, packaging, automobile parts IDEMITSU KOSAN CO., LTD. (JP) 1993-10-05 US disclosed
EP-0559108-A1 Graft copolymer, process for production thereof and resin composition containing same IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-09-08 EP disclosed
EP-0511407-A1 STYRENIC COPOLYMER AND PRODUCTION THEREOF IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-11-04 EP disclosed
EP-0505997-A2 Process for producing styrenic polymer and copolymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-09-30 EP disclosed
EP-0490269-A1 Graft copolymer and process for producing the same IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-06-17 EP disclosed