Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8370673 | 0.83 | HTR2A (0.31) | — | |
| SCHEMBL7039663 | 0.83 | GABRA1 (0.34) | GABRA1GABRB2ELANEKDM4EMEN1 | |
| SCHEMBL1451567 | 0.82 | — | — | |
| SCHEMBL27495345 | 0.79 | GABRA1 (0.33) | GABRA1GABRB2ELANE | |
| SCHEMBL5836913 | 0.78 | ADRB2 (0.33) | — | |
| SCHEMBL7034550 | 0.76 | SYK (0.33) | MAPT | |
| SCHEMBL7038530 | 0.76 | EDNRB (0.35) | — | |
| SCHEMBL27543131 | 0.76 | GABRA1 (0.36) | GABRA1GABRB2KDM4EMEN1MAPT | |
| SCHEMBL27524796 | 0.76 | GABRA1 (0.36) | GABRA1GABRB2KDM4EMEN1MAPT | |
| SCHEMBL28411828 | 0.76 | GABRA1 (0.36) | GABRA1GABRB2KDM4EMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620953-B1 | Complexing dimethylbis(2-methyl-4,5-benzoindenyl)silane with transition metal compounds such as 2,4-di-tert-butylphenoxide, zirconium monochloride, to form polymerization catalysts | BASSELL POLYOLEFINE GMBH (DE) | 2003-09-16 | — | — | US | disclosed |
| EP-1133504-B1 | METHOD FOR PRODUCING MONOARYLOXY-ANSA-METALLOCENES | BASELL POLYOLEFINE GMBH (DE) | 2003-03-12 | — | — | EP | disclosed |