Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | CASR | P41180 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7036418 | 0.90 | BRD4 (0.31) | BRD4CREBBPCASR | |
| SCHEMBL7200224 | 0.90 | NR3C1 (0.32) | — | |
| SCHEMBL7196903 | 0.89 | BRD4 (0.31) | BRD4CREBBP | |
| SCHEMBL7036050 | 0.88 | UCHL3 (0.34) | CASR | |
| SCHEMBL7034550 | 0.85 | SYK (0.33) | MAPT | |
| SCHEMBL7038530 | 0.85 | EDNRB (0.35) | NOTUM | |
| SCHEMBL5836913 | 0.85 | ADRB2 (0.33) | — | |
| SCHEMBL7031845 | 0.83 | BRD4 (0.33) | BRD4CREBBPMEN1USP2LMNA | |
| SCHEMBL7034367 | 0.83 | BRD4 (0.33) | BRD4CREBBPMEN1USP2LMNA | |
| SCHEMBL7196862 | 0.82 | SMN1; SMN2 (0.34) | BRD4CREBBPLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620953-B1 | Complexing dimethylbis(2-methyl-4,5-benzoindenyl)silane with transition metal compounds such as 2,4-di-tert-butylphenoxide, zirconium monochloride, to form polymerization catalysts | BASSELL POLYOLEFINE GMBH (DE) | 2003-09-16 | — | — | US | disclosed |
| EP-1133504-B1 | METHOD FOR PRODUCING MONOARYLOXY-ANSA-METALLOCENES | BASELL POLYOLEFINE GMBH (DE) | 2003-03-12 | — | — | EP | disclosed |