Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.45 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.40 |
| ▸ | PYGL | P06737 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7036665 | 1.00 | CTSK (0.53) | CTSKHDAC4MEF2DSLC6A5HDAC1 | |
| SCHEMBL7036651 | 0.87 | SLC6A5 (0.52) | CTSKHDAC4MEF2DSLC6A5HDAC1 | |
| SCHEMBL4404268 | 0.86 | CTSK (0.64) | CTSKHDAC4MEF2DHDAC1FOLH1 | |
| SCHEMBL8772974 | 0.86 | CTSK (0.64) | CTSKHDAC4MEF2DHDAC1FOLH1 | |
| SCHEMBL825451 | 0.86 | CTSK (0.64) | CTSKHDAC4MEF2DHDAC1FOLH1 | |
| SCHEMBL22449378 | 0.75 | MLYCD (0.49) | CTSK | |
| SCHEMBL20341491 | 0.75 | KDM4E (0.51) | HDAC4HDAC1HDAC3HDAC7HDAC2 | |
| SCHEMBL20341502 | 0.75 | KDM4E (0.51) | HDAC4HDAC1HDAC3HDAC7HDAC2 | |
| SCHEMBL8177757 | 0.73 | SMN1; SMN2 (0.60) | CTSKHDAC4HDAC1GRIA1HDAC3 | |
| SCHEMBL27883407 | 0.73 | KMT2A (0.53) | CTSKPSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0822827-B1 | ANTAGONISTS OF LHRH | UNIV TEXAS (US) | 2003-03-05 | — | — | EP | disclosed |
| EP-0822827-A4 | ANTAGONISTS OF LHRH | UNIV TEXAS (US) | 2001-07-11 | — | — | EP | disclosed |
| EP-0822827-A1 | ANTAGONISTS OF LHRH | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1998-02-11 | — | — | EP | disclosed |
| WO-1996033729-A1 | ANTAGONISTS OF LHRH | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1996-10-31 | — | — | WO | disclosed |