Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.64 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.45 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL825451 | 1.00 | CTSK (0.64) | CTSKGRIA1HDAC4MEF2DEPHX2 | |
| SCHEMBL4404268 | 1.00 | CTSK (0.64) | CTSKGRIA1HDAC4MEF2DEPHX2 | |
| SCHEMBL7036665 | 0.86 | CTSK (0.53) | CTSKGRIA1HDAC4MEF2DHDAC1 | |
| SCHEMBL7036660 | 0.86 | CTSK (0.53) | CTSKGRIA1HDAC4MEF2DHDAC1 | |
| SCHEMBL8177757 | 0.86 | SMN1; SMN2 (0.60) | CTSKGRIA1HDAC4EPHX2HDAC1 | |
| SCHEMBL8861463 | 0.85 | EPHX2 (0.50) | CTSKGRIA1HDAC4EPHX2HDAC1 | |
| SCHEMBL8177140 | 0.85 | SMN1; SMN2 (0.59) | CTSKGRIA1HDAC4EPHX2HDAC1 | |
| SCHEMBL7036651 | 0.83 | SLC6A5 (0.52) | CTSKHDAC4MEF2DHDAC1SMN1; SMN2 | |
| SCHEMBL7034276 | 0.83 | P2RX7 (0.52) | CTSKMMP2MMP9FOLH1ERAP2 | |
| SCHEMBL7034270 | 0.83 | P2RX7 (0.52) | CTSKMMP2MMP9FOLH1ERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800535-A1 | FIBRONECTIN ADHESION INHIBITORS | ZENECA LIMITED (GB) | 1997-10-15 | — | — | EP | claimed |
| WO-1996020216-A1 | FIBRONECTIN ADHESION INHIBITORS | ZENECA LIMITED (GB) | 1996-07-04 | — | — | WO | claimed |
| EP-0800535-A1 | FIBRONECTIN ADHESION INHIBITORS | ZENECA LIMITED (GB) | 1997-10-15 | — | — | EP | disclosed |
| WO-1996020216-A1 | FIBRONECTIN ADHESION INHIBITORS | ZENECA LIMITED (GB) | 1996-07-04 | — | — | WO | disclosed |